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Altered proliferation and differentiation properties of primary mammary epithel…

Burga(Laura N),Tung(Nadine M),Troyan(Susan L… Cancer Res 2009-03-24

...BRCA1 by immunohistochemistry, and 79% of the examined single colonies from BRCA1 carriers retained heterozygosity for B...

Maintenance of the DNA-damage checkpoint requires DNA-damage-induced mediator p…

Usui(Takehiko),Foster(Steven S),Petrini(John… Mol Cell 2009-03-04

...Brca1 C-terminal (BRCT) domain-containing mediator proteins occurs at sites of DNA damage. However, the functional signi...

Cell-free tumor DNA in blood plasma as a marker for circulating tumor cells in …

Schwarzenbach(Heidi),Alix-Panabières(Catheri… Clin Cancer Res 2009-07-16

...BRCA1, respectively, were observed.,These findings show, for the first time, a relationship between the occurrence of CT...

Associations of high-grade prostate cancer with BRCA1 and BRCA2 founder mutatio…

Agalliu(Ilir),Gern(Robert),Leanza(Suzanne),B… Clin Cancer Res 2009-07-16

...BRCA1 mutations were not associated with prostate cancer, the BRCA1-185delAG was associated with high Gleason score tumo...

Association of C-terminal ubiquitin hydrolase BRCA1-associated protein 1 with c…

Misaghi(Shahram),Ottosen(Søren),Izrael-Tomas… Mol Cell Biol 2009-04-22

...BRCA1-associated protein-1 (Bap1) is a ubiquitin carboxy-terminal hydrolase and is frequently mutated in lung and sporad...

BRCA1 and BRCA2 mutations in women of different ethnicities undergoing testing …

Hall(Michael J),Reid(Julia E),Burbidge(Lynn … Cancer 2009-06-16

...BRCA1) and BRCA2 has important implications for screening and prevention counseling. Uncertainty regarding the role of B...

Race, genetic West African ancestry, and prostate cancer prediction by prostate…

Giri(Veda N),Egleston(Brian),Ruth(Karen),Uzz… Cancer Prev Res (Phila) 2009-08-14

...BRCA1/2 mutations. Biopsies were done at low PSA values (<4.0 ng/mL). WA ancestry was discerned by genotyping 100 ancest...

Precursors to pelvic serous carcinoma and their clinical implications.

Folkins(Ann K),Jarboe(Elke A),Roh(Michael H)… Gynecol Oncol 2009-05-18

...BRCA1 or BRCA2 mutations (BRCA+) undergoing risk reducing salpingo-oophorectomy have highlighted the distal fallopian tu...

The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at…

Stewart(Grant S),Panier(Stephanie),Townsend(… Cell 2009-02-23

...BRCA1 to DNA lesions, and their loss is the likely cause of the cellular and developmental phenotypes associated with RI...

The potential role and application of PARP inhibitors in cancer treatment.

Chalmers(Anthony J) Br Med Bull 2009-10-05

...BRCA1- and BRCA2-deficient cancers, and in combination they increase the cytotoxic effects of certain chemotherapy agent...

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