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Inactivation of the Nijmegen breakage syndrome gene leads to excess centrosome …

Shimada(Mikio),Sagae(Ruri),Kobayashi(Junya),… Cancer Res 2009-03-20

...BRCA1-inhibited cells. In fact, supernumerary centrosomes were observed in Brca1 knockout mouse cells, and the frequency...

The 4154delA mutation carriers in the BRCA1 gene share a common ancestry.

Ozolina(Silvija),Sinicka(Olga),Jankevics(Eri… Fam Cancer 2009-04-30

Uncertainty exists whether the 4154delA mutation of the BRCA1 gene detected in unrelated individuals from Latvia, Poland...

A BRCA1 mutation is not associated with increased indicators of oxidative stres…

Kotsopoulos(Joanne),Shen(HongLei),Rao(A Venk… Clin Breast Cancer 2009-02-19

...BRCA1 protein. A recent study suggests that BRCA1 is involved in the cellular antioxidant response by inducing the expre...

Prolactin blocks nuclear translocation of VDR by regulating its interaction wit…

Deng(Changhui),Ueda(Eric),Chen(Kuanhui E),Bu… Mol Endocrinol 2009-03-24

...BRCA1, by Western blot of the VDR immunoprecipitate and confirmed by immunoprecipitation with anti-BRCA1 and blotting fo...

Expression of breast cancer resistance protein is associated with a poor clinic…

Kim(Young Hak),Ishii(Genichiro),Goto(Koichi)… Lung Cancer 2009-09-18

...BRCA1) protein, in tumor biopsy specimens obtained before chemotherapy from 130 SCLC patients who later received platinu...

Effect of BRCA1 haplotype on survival of non-small-cell lung cancer patients tr…

Kim(Hong-Tae),Lee(Jong-Eun),Shin(Eun-Soon),Y… J Clin Oncol 2009-01-13

To determine whether germ-line variations in BRCA1 affect outcome in non-small-cell lung cancer (NSCLC) patients treated...

Uptake of clinical genetic testing for ovarian cancer in Ontario: a population-…

Metcalfe(Kelly A),Fan(Isabel),McLaughlin(Joh… Gynecol Oncol 2009-01-02

...BRCA1 or BRCA2. In 2001, genetic testing for BRCA1 and BRCA2 became freely available to all women in Ontario with a diag...

Physicians' experiences with BRCA1/2 testing in community settings.

Keating(Nancy L),Stoeckert(Kathryn A),Regan(… J Clin Oncol 2009-01-06

We surveyed a national sample of nonacademic physicians who ordered BRCA1/2 testing to understand their implementation o...

Intraepithelial T cells and prognosis in ovarian carcinoma: novel associations …

Clarke(Blaise),Tinker(Anna V),Lee(Cheng-Han)… Mod Pathol 2009-05-26

...BRCA1 mutation status and expression. Intraepithelial immune cells were assessed as present or absent by immunohistochem...

Inhibition of CHK1 kinase by Gö6976 converts 8-chloro-adenosine-induced G2/M ar…

Jia(Xiu-Zhen),Yang(Sheng-Yong),Zhou(Jing),Li… Biochem Pharmacol 2009-03-20

...BRCA1-CHK1 branch in apoptosis-resistant human myelocytic leukemia K562 (p53-null) cells. Inhibition of CHK1 kinase by G...

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