...BRCA1 deficiency. Intriguingly, the increased sensitivity to these compounds displayed by BRCA1-defective cells was not ...
...BRCA1. Recently, it was found to modulate the nuclease activity of the Mre11/Rad50/NBS1 complex. Here we report that CtI...
...BRCA1) and chromatin remodeling complexes (INO80, SWR1, TIP60-p400) at DSBs. These collectively regulate DSB repair and ...
...BRCA1 gene mutation carriers.,Thirty BRCA1 gene female mutation carriers aged 21-39 years, citizens of Szczecin, have be...
Prophylactic adnexectomy is widely used for cancer risk reduction in women with BRCA1 gene mutations. Adnexectomy signif...
...BRCA1, BRCA2 and CHEK2 gene mutations with reference to their positive family history of cancer.,The DNA of peripheral b...
...BRCA1 and 53BP1, to sites of DNA damage suggests that these two E3 ligases define a ubiquitylation cascade that regulate...
...BRCA1, and serves as the molecular scaffold in the formation of the BRCA1-PALB2-BRCA2 complex. The association between B...
...BRCA1 5382insC mutation while the remaining 2 sisters carried paternal BRCA1 1629delC allele. No BRCA1 homozygous mutati...
...BRCA1 5382insC, BRCA1 4153delA, BRCA1 185delAG, BRCA1 300T>G, BRCA2 6174delT, CHEK2 1100delC, CHEK2 IVS2+1G>A, NBS1 657d...
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