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Premature senescence is a major response to DNA cross-linking agents in BRCA1-d…

Santarosa(Manuela),Del Col(Laura),Tonin(Elen… Mol Cancer Ther 2009-06-08

...BRCA1 deficiency. Intriguingly, the increased sensitivity to these compounds displayed by BRCA1-defective cells was not ...

Expression of PCNA-binding domain of CtIP, a motif required for CtIP localizati…

Gu(Bingnan),Chen(Phang-Lang) Cell Cycle 2009-06-03

...BRCA1. Recently, it was found to modulate the nuclease activity of the Mre11/Rad50/NBS1 complex. Here we report that CtI...

Crosstalk between histone modifications during the DNA damage response.

van Attikum(Haico),Gasser(Susan M) Trends Cell Biol 2009-06-26

...BRCA1) and chromatin remodeling complexes (INO80, SWR1, TIP60-p400) at DSBs. These collectively regulate DSB repair and ...

[Evaluation of stomatognathic system in BRCA1 gene mutation carriers before and…

Chruściel-Nogalska(Małgorzata) Ann Acad Med Stetin 2009-05-08

...BRCA1 gene mutation carriers.,Thirty BRCA1 gene female mutation carriers aged 21-39 years, citizens of Szczecin, have be...

[Evaluation of stomatognathic system in BRCA1 gene mutation carriers before and…

Chruściel-Nogalska(Małgorzata) Ann Acad Med Stetin 2009-05-08

Prophylactic adnexectomy is widely used for cancer risk reduction in women with BRCA1 gene mutations. Adnexectomy signif...

Age at onset of bilateral breast cancer, the presence of hereditary BRCA1, BRCA…

Skasko(Elzbieta),Kluska(Anna),Niwińska(Anna)… Onkologie 2009-06-16

...BRCA1, BRCA2 and CHEK2 gene mutations with reference to their positive family history of cancer.,The DNA of peripheral b...

Solving the RIDDLE of 53BP1 recruitment to sites of damage.

Stewart(Grant S) Cell Cycle 2009-10-13

...BRCA1 and 53BP1, to sites of DNA damage suggests that these two E3 ligases define a ubiquitylation cascade that regulate...

PALB2 is an integral component of the BRCA complex required for homologous reco…

Sy(Shirley M H),Huen(Michael S Y),Chen(Junji… Proc Natl Acad Sci U S A 2009-06-05

...BRCA1, and serves as the molecular scaffold in the formation of the BRCA1-PALB2-BRCA2 complex. The association between B...

Large family with both parents affected by distinct BRCA1 mutations: implicatio…

Sokolenko(Anna P),Voskresenskiy(Dmitry A),Iy… Hered Cancer Clin Pract 2009-12-29

...BRCA1 5382insC mutation while the remaining 2 sisters carried paternal BRCA1 1629delC allele. No BRCA1 homozygous mutati...

High frequency of BRCA1, but not CHEK2 or NBS1 (NBN), founder mutations in Russ…

Suspitsin(Evgeny N),Sherina(Nathalia Yu),Pon… Hered Cancer Clin Pract 2009-12-29

...BRCA1 5382insC, BRCA1 4153delA, BRCA1 185delAG, BRCA1 300T>G, BRCA2 6174delT, CHEK2 1100delC, CHEK2 IVS2+1G>A, NBS1 657d...

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