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Survival in Norwegian BRCA1 mutation carriers with breast cancer.

Hagen(Anne Irene),Tretli(Steinar),Maehle(Lov… Hered Cancer Clin Pract 2009-12-29

...BRCA1 mutation carriers.One hundred and sixty-seven women with disease-associated germline BRCA1 mutations and breast ca...

BRCA1 breast cancer risk is modified by CYP19 polymorphisms in Ashkenazi Jews.

Raskin(Leon),Lejbkowicz(Flavio),Barnett-Grin… Cancer Epidemiol Biomarkers P… 2009-06-25

...BRCA1 carriers ages <50 years (odds ratio, 2.81; 95% confidence interval, 1.09-7.22; P = 0.032) but not in BRCA2 carrier...

BRCA1 down-regulates cellular levels of reactive oxygen species.

Saha(Tapas),Rih(Jeong Keun),Rosen(Eliot M) FEBS Lett 2009-05-28

...BRCA1 could modulate intracellular levels of reactive oxygen species (ROS). Wild-type BRCA1 (but not a cancer-associated...

Breast cancer therapy for BRCA1 carriers: moving towards platinum standard?

Imyanitov(Evgeny N) Hered Cancer Clin Pract 2009-12-29

Recently Byrski et al. reported the first-ever breast cancer (BC) study, which specifically selected BRCA1-carriers for ...

Genetic alterations detected by comparative genomic hybridization and recurrenc…

Bruchim(Ilan),Israeli(Ofir),Mahmud(Salaheddi… Cancer Genet Cytogenet 2009-06-25

...BRCA1 and BRCA2 mutation carriers, respectively. Relevant clinical data, including histology, grade, stage, size of resi...

DNA methylation profile in diffuse type gastric cancer: evidence for hypermethy…

Bernal(Carolina),Vargas(Macarena),Ossandón(F… Biol Res 2009-10-07

...BRCA1 and APC (>50%), followed by p14, p16, p15, p73, MGMT and SEMA3B (20-49%). Hierarchical clustering analysis reveals...

Brca1 is required for embryonic development of the mouse cerebral cortex to nor…

Pulvers(Jeremy N),Huttner(Wieland B) Development 2009-11-13

...Brca1, the ortholog of the human breast cancer susceptibility gene BRCA1, show apoptosis in the neural tube, but the con...

Cisplatin-induced DNA damage activates replication checkpoint signaling compone…

Wagner(Jill M),Karnitz(Larry M) Mol Pharmacol 2009-07-17

...BRCA1, BRCA2, or FancD2 was disabled, Chk1 depletion did not further sensitize the cells to cisplatin. In fact, Chk1 dep...

Association of hormone receptor status with grading, age of onset, and tumor si…

Graeser(M),Bosse(K),Brosig(M),Engel(C),Schmu… Virchows Arch 2009-07-28

BRCA1-associated breast cancer frequently presents with estrogen-receptor (ERalpha) and progesterone-receptor (PR) negat...

Study designs in genetic epidemiology.

Cote(Michele L) Methods Mol Biol 2009-05-20

...BRCA1, BRCA2, APC, MLH1, MSH2, and MSH6 have been identified in families with a large number of relatives who have been ...

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