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Candidate serous cancer precursors in fallopian tube epithelium of BRCA1/2 muta…

Shaw(Patricia A),Rouzbahman(Marjan),Pizer(El… Mod Pathol 2009-11-10

...BRCA1/2, and without histological examination of the entire tube, and cases with a diagnosis of invasive carcinoma. Cont...

Cancers in BRCA1 and BRCA2 carriers and in women at high risk for breast cancer…

Gilbert(Fiona J),Warren(Ruth M L),Kwan-Lim(G… Radiology 2009-09-15

...BRCA1 and BRCA2 carriers and in women with a high risk for breast cancer.,Informed consent and multicenter and local res...

Functional interaction between the Fanconi Anemia D2 protein and proliferating …

Howlett(Niall G),Harney(Julie A),Rego(Meghan… J Biol Chem 2009-11-24

...BRCA1 and FANCD1/BRCA2, function cooperatively in the FA-BRCA pathway to repair damaged DNA and to prevent cellular tran...

Multimodal assessment of protein functional deficiency supports pathogenicity o…

De Nicolo(Arcangela),Parisini(Emilio),Zhong(… Cancer Res 2009-11-17

...BRCA1 p.V1688del. Consistently, the recombinant DeltaValBRCA1 was less stable than wild-type BRCA1 and, unlike the latte...

The TP53 Arg72Pro and MDM2 309G>T polymorphisms are not associated with breast …

Sinilnikova(O M),Antoniou(A C),Simard(J),Hea… Br J Cancer 2009-10-28

...BRCA1- and BRCA2-mediated carcinogenesis. A single nucleotide polymorphism (SNP) in the promoter region of MDM2 (309T>G,...

BARD1 may be renamed ROW1 because it functions mainly as a REPRESSOR OF WUSCHEL…

Han(Pei),Zhu(Yu-Xian) Plant Signal Behav 2009-11-23

...BRCA1-Associated Ring Domain 1) forms heterodimer via its N-terminal conserved RING domain with BRCA1. In Arabidopsis, t...

Moderate increase in Mdr1a/1b expression causes in vivo resistance to doxorubic…

Pajic(Marina),Iyer(Jayasree K),Kersbergen(Ar… Cancer Res 2009-09-15

...BRCA1-related breast cancer was associated with increased expression of the mouse multidrug resistance (Mdr1) genes, whi...

Elucidation of the transmission of a novel mutation in BRCA1 (1125delCT) in a f…

Razis(Evangelia),Belogianni(Ioulia),Siamanta… Cancer Genomics Proteomics 2009-12-30

...BRCA1. Three out of three offsprings have the novel mutation while the mother affected by breast cancer does not carry t...

Uptake of risk-reducing surgery in unaffected women at high risk of breast and …

Evans(D Gareth R),Lalloo(Fiona),Ashcroft(Lin… Cancer Epidemiol Biomarkers P… 2009-10-20

...BRCA1/2 mutation carriers from 509 families and in 3,515 women at >25% lifetime risk of breast cancer without known muta...

Missense polymorphisms in BRCA1 and BRCA2 and risk of breast and ovarian cancer.

Dombernowsky(Sarah Louise),Weischer(Maren),F… Cancer Epidemiol Biomarkers P… 2009-10-20

BRCA1 and BRCA2 are key tumor suppressors with a role in cellular DNA repair, genomic stability, and checkpoint control....

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