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TP53 BRCA1 CRISPR single-cell cancer

Kurian(Allison W),Gong(Gail D),John(Esther M… Cancer Epidemiol Biomarkers P… 2009-06-16

...BRCA1 or BRCA2. Accurate carrier prediction models are needed to target costly testing. Two widely used models, BRCAPRO ...

Loud(Jennifer T),Thiébaut(Anne C M),Abati(An… Cancer Epidemiol Biomarkers P… 2009-06-16

...BRCA1/2 = 146, mutation-negative = 23, untested = 2). Fisher's exact test was used to evaluate categorical variables; Wi...

Holstege(Henne),Joosse(Simon A),van Oostrom(… Cancer Res 2009-06-19

...BRCA1-related breast cancers suggests that p53 loss of function is essential for BRCA1-associated tumorigenesis. BRCA1-r...

Tassone(Pierfrancesco),Di Martino(Maria Tere… Cancer Biol Ther 2009-08-27

...BRCA1-defective HCC1937 or BRCA1-reconstituted HCC1937/(WT)BRCA1 human breast cancer xenografts (HBCXs) generated in SCI...

Peralta-Leal(Andreína),Rodríguez-Vargas(José… Free Radic Biol Med 2009-12-17

...BRCA1 and BRCA2). PARP becomes activated in response to oxidative DNA damage and depletes cellular energy pools, thus le...

Schmidt(Marjanka K),Vermeulen(Eric),Tollenaa… Eur J Cancer 2009-09-15

In a large retrospective cohort of breast cancer patients, BRCA1 and BRCA2 germline mutations were analysed in DNA isola...

Saha(Tapas),Rih(Jeong Keun),Rosen(Eliot M) FEBS Lett 2009-05-28

...BRCA1 could modulate intracellular levels of reactive oxygen species (ROS). Wild-type BRCA1 (but not a cancer-associated...

James(Edward),Waldron-Lynch(Maeve G),Saif(Mu… Anticancer Drugs 2009-09-11

...BRCA1 and BRCA2 have been proven to predict a drastically increased lifetime risk of breast and ovarian cancers in the i...

Drikos(Ioannis),Nounesis(George),Vorgias(Con… Proteins 2009-11-17

...BRCA1 is involved in DNA repair and cell cycle control. Mutations at the two C-terminal tandem (BRCT) repeats of BRCA1 d...

Song(Chuan-gui),Hu(Zhen),Yuan(Wen-tao),Di(Ge… Zhonghua Yi Xue Yi Chuan Xue … 2009-03-24

...BRCA1/2 mutant.,One hundred and fourteen BRCA1/2 -negative hereditary breast cancer patients from independent families a...

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