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Preclinical mouse models for BRCA1-associated breast cancer.

Drost(R M),Jonkers(J) Br J Cancer 2009-12-24

...BRCA1 germline mutations. In this review, we will discuss the insights into BRCA1 functions that we obtained from mouse ...

Mutational analysis of BRCA1 and BRCA2 genes in Mexican breast cancer patients.

Vidal-Millán(S),Taja-Chayeb(L),Gutiérrez-Her… Eur J Gynaecol Oncol 2009-12-08

Germline mutations in the BRCA1 and BRCA2 genes predispose to breast and ovarian cancer. A variable incidence of mutatio...

Multistep level sections to detect occult fallopian tube carcinoma in risk-redu…

Rabban(Joseph T),Krasik(Ellen),Chen(Lee-May)… Am J Surg Pathol 2009-12-11

...BRCA1 or BRCA2 germline mutations. A minority of RRSO specimens from these women will contain occult early-stage carcino...

BRCA1 and BRCA2 germline mutation analysis among Indian women from south India:…

Vaidyanathan(Kannan),Lakhotia(Smita),Ravisha… J Biosci 2009-12-29

...BRCA1 mutations and two (3.28%) had BRCA2 mutations. While no specific association between BRCA1 or BRCA2 mutations with...

Impact of androgen receptor cytosine-adenine-guanine polymorphisms on clinical …

Li(Andrew J),McAllister(Paula),Karlan(Beth Y) Gynecol Oncol 2009-12-11

...BRCA1/2 mutation positive women with ovarian cancer.,We identified BRCA1/2 ovarian cancer patients with banked serum fro...

Family history of cancer rather than p53 status predicts efficacy of pegylated …

Nicoletto(Maria Ornella),Bertorelle(Roberta)… Int J Gynecol Cancer 2009-12-29

...BRCA1/2 and TP53 status and overall survival (OS) were determined. Thirty-eight had a short platinum-free interval (PFI;...

Fatigue and quality of life after risk-reducing salpingo-oophorectomy in women …

Michelsen(Trond M),Dørum(Anne),Tropé(Claes G… Int J Gynecol Cancer 2009-12-29

...BRCA1/2 carriers and women with unknown mutation statuses. Women who had cancer (32%), however, showed clinically signif...

Characteristics of health information gatherers, disseminators, and blockers wi…

Koehly(Laura M),Peters(June A),Kenen(Regina)… Am J Public Health 2009-12-07

...BRCA1/2 genes (associated with high risk of breast, ovarian, and other types of cancer) were identified by using the Col...

Limiting the persistence of a chromosome break diminishes its mutagenic potenti…

Bennardo(Nicole),Gunn(Amanda),Cheng(Anita),H… PLoS Genet 2009-12-11

...Brca1 in a set of distinct repair events. Subsequently, we considered that the outcome of such assays could be influence...

Human papillomaviruses activate the ATM DNA damage pathway for viral genome amp…

Moody(Cary A),Laimins(Laimonis A) PLoS Pathog 2009-12-16

...BRCA1 and NBS1. This activation is necessary for viral genome amplification, as well as for formation of viral replicati...

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