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Gene expression profiling integrated into network modelling reveals heterogenei…

Fernández-Ramires(R),Solé(X),De Cecco(L),Llo… Br J Cancer 2009-10-28

...BRCA1 germline mutation.,This study reveals the molecular complexity of BRCA1 breast tumours, which are found to display...

Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and …

Marteijn(Jurgen A),Bekker-Jensen(Simon),Mail… J Cell Biol 2009-10-15

...Brca1. Although both lesions are processed by independent repair pathways and trigger signaling responses by distinct ki...

The deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF…

Machida(Yuichi J),Machida(Yuka),Vashisht(Aja… J Biol Chem 2009-12-22

...BRCA1-associated protein 1 (BAP1) possesses growth inhibitory activity and functions as a tumor suppressor. In this stud...

Germline mutations in MEN1 and BRCA1 genes in a woman with familial multiple en…

Papi(Laura),Palli(Domenico),Masi(Laura),Puti… Cancer Genet Cytogenet 2009-11-12

...BRCA1 mutation, except for the development of an extremely large visceral lipoma; the proband has not developed any BRCA...

Prepubertal octylphenol exposure up-regulate BRCA1 expression, down-regulate ER…

Peng(Jun-Hua),Zhang(Feng),Zhang(Hua-Xing),Fa… Cancer Epidemiol 2009-09-30

...BRCA1 mRNA in mammary gland and reduce futuer breast cancer risk. In the present study, the effects of prepubertal expos...

Elucidation of the transmission of a novel mutation in BRCA1 (1125delCT) in a f…

Razis(Evangelia),Belogianni(Ioulia),Siamanta… Cancer Genomics Proteomics 2009-12-30

...BRCA1. Three out of three offsprings have the novel mutation while the mother affected by breast cancer does not carry t...

Missense polymorphisms in BRCA1 and BRCA2 and risk of breast and ovarian cancer.

Dombernowsky(Sarah Louise),Weischer(Maren),F… Cancer Epidemiol Biomarkers P… 2009-10-20

BRCA1 and BRCA2 are key tumor suppressors with a role in cellular DNA repair, genomic stability, and checkpoint control....

Uptake of risk-reducing surgery in unaffected women at high risk of breast and …

Evans(D Gareth R),Lalloo(Fiona),Ashcroft(Lin… Cancer Epidemiol Biomarkers P… 2009-10-20

...BRCA1/2 mutation carriers from 509 families and in 3,515 women at >25% lifetime risk of breast cancer without known muta...

Cellular and molecular consequences of defective Fanconi anemia proteins in rep…

Thompson(Larry H),Hinz(John M) Mutat Res 2009-09-29

...BRCA1 and may remove structural barriers to replication, such as guanine quadruplex structures, and/or assist in crossli...

Comprehensive mutational analysis of BRCA1/BRCA2 for Korean breast cancer patie…

Seong(M-W),Cho(Si),Noh(D-Y),Han(W),Kim(S-W),… Clin Genet 2009-12-09

...BRCA1 and BRCA2 genes are the strongest susceptibility genes identified for breast cancer worldwide. However, BRCA1/BRCA...

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