...BRCA1 proteins. We have mapped BRCA1 [within amino acids (aa) 1-182] as the minimum domain that is sufficient for in vit...
...BRCA1, 14-3-3sigma, DNA-PK and MGMT mRNA, and ATM and MGMT mRNA expression were inhibited in a time-dependent manner. Ou...
Mutation of the breast and ovarian cancer specific tumor suppressor, BRCA1, results in supernumerary and hyperactive cen...
...BRCA1 and BRCA2 mutant tumor cells showed high levels of centriole splitting in the absence of any treatment. IR caused ...
...BRCA1 associates with BRCA2 through PALB2/FANCN, a major binding partner of BRCA2. The interaction between BRCA1 and BRC...
It is often recommended that women who carry a mutation in the BRCA1 or BRCA2 gene have their ovaries and fallopian tube...
Although the increase in risk of developing breast, ovarian, and prostate cancer in BRCA1 and BRCA2 mutation carriers ha...
...BRCA1/2 mutations. Biopsies were done at low PSA values (<4.0 ng/mL). WA ancestry was discerned by genotyping 100 ancest...
...BRCA1 mutation carriers, in young women and in African-American women. The reasons for these associations are unclear bu...
...BRCA1/2 mutation analysis was conducted on all patients who contracted pelvic cancer.,We identified 1,582 women at risk ...
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