...BRCA1 and BRCA2). PARP becomes activated in response to oxidative DNA damage and depletes cellular energy pools, thus le...
In a large retrospective cohort of breast cancer patients, BRCA1 and BRCA2 germline mutations were analysed in DNA isola...
...BRCA1 or BRCA2 genes, both of which confer an increased lifetime risk for ovarian, tubal, peritoneal, and breast cancer....
...BRCA1 status in breast cancer cells. We provide evidence that in breast cancer cells BRCA1 is involved in XIST regulatio...
...BRCA1/2 testing; and 18% had used a software program to calculate breast cancer risk. Physicians who had used BRCA1/2 te...
...BRCA1 and this gene is discussed in detail with reference to chemotherapy response in cell lines and in the clinical tre...
Inheritance of a mutation in BRCA1 (breast cancer 1 early-onset) results in predisposition to early-onset breast and ova...
...BRCA1 gene mutations had not been clearly understood. Of significance is the finding that BRCA1 negatively regulates aro...
Accumulating studies indicate that HPV E6/E7 oncoproteins interacting genes, TP53, BRCA1 and BARD1, play a critical role...
...BRCA1 and BRCA2 can have emotional consequences for both the tested individual and his or her relatives. This secondary ...
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