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Novel complex genomic rearrangement of the BRCA1 gene.

Zikan(Michal),Pohlreich(Petr),Stribrna(Jana)… Mutat Res 2008-03-13

...BRCA1/2 genes in the Czech population, we have detected a complex genomic rearrangement in BRCA1 using RNA-based analysi...

Minimal deletion regions in lung squamous cell carcinoma: association with abno…

Tseng(Ruo-Chia),Hsieh(Feng-Jen),Hsu(Han-Shui… Lung Cancer 2008-09-23

...BRCA1 and XRCC5, are involved in patients with high FAL. In addition, chromosomal deletion analysis enables the delineat...

ERCC1 protein expression predicts the response of cisplatin-based neoadjuvant c…

Fujii(Tetsuya),Toyooka(Shinichi),Ichimura(Ko… Lung Cancer 2008-09-23

The excision repair cross-complementation group 1 (ERCC1) and BRCA1 have been identified as predictors of clinical outco...

The predominant role of surgery in the prevention and new trends in the surgica…

Fatouros(Michael),Baltoyiannis(Georgios),Rou… Ann Surg Oncol 2008-02-21

...BRCA1 or BRCA2 germ-line mutation are at very high risk of breast and/or ovarian cancer. Because high-quality data are l...

G:C > A:T mutations and potential epigenetic regulation of p53 in breast cancer.

Kouidou(Sofia),Malousi(Andigoni),Kyventidis(… Breast Cancer Res Treat 2008-01-24

...BRCA1, or BRCA2-related), but frequent in sporadic cancers in organs where Li-Fraumeni-related carcinogenesis is common ...

A multigenic study on breast cancer risk associated with genetic polymorphisms …

Hu(Zhen),Song(Chuan-Gui),Lu(Jing-Song),Luo(J… J Cancer Res Clin Oncol 2008-03-06

High penetrance genes such as BRCA1 or BRCA2 account for only a small proportion of familial breast cancer in Chinese po...

Prophylactic mastectomy in BRCA1/2 mutation carriers and women at risk of hered…

Heemskerk-Gerritsen(Bernadette A M),Brekelma… Ann Surg Oncol 2008-01-31

BRCA1/2 mutation carriers and women from a hereditary breast(/ovarian) cancer family have a highly increased risk of dev...

Germline TP53 mutations in BRCA1 and BRCA2 mutation-negative French Canadian br…

Arcand(Suzanna L),Maugard(Christine M),Ghadi… Breast Cancer Res Treat 2008-06-24

...BRCA1 or BRCA1 mutations where common mutations account for about 84% of all mutations identified in cancer families. Wi...

Heterogenic loss of the wild-type BRCA allele in human breast tumorigenesis.

King(Tari A),Li(Weiwei),Brogi(Edi),Yee(Cindy… Ann Surg Oncol 2008-01-24

...BRCA1 or BRCA2 were identified. After pathologic review, focal areas of normal breast epithelium, atypical ductal hyperp...

Distinct BRCT domains in Mcph1/Brit1 mediate ionizing radiation-induced focus f…

Jeffers(L J),Coull(B J),Stack(S J),Morrison(… Oncogene 2008-01-22

...Brca1 or Chk1. cMcph1 formed IRIF in ATM- and Brca1-deficient cells, but not in H2AX-deficient cells. Inability to form ...

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