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Development and pilot evaluation of novel genetic educational materials designe…

Lubitz(Rebecca Jean),Komaromy(Miriam),Crawfo… Genet Test 2008-01-15

...BRCA1 and BRCA2 mutations involves teaching about hereditary cancer, genetics and risk, subjects that are difficult to g...

Overlapping gene expression profiles of model compounds provide opportunities f…

Baken(Kirsten A),Pennings(Jeroen L A),Jonker… Toxicol Appl Pharmacol 2008-02-05

...Brca1, Birc5, Incenp, and Cdkn1a (p21) were identified as candidate genes to indicate anti-proliferative effects of xeno...

Role played by BRCA1 in transcriptional regulation in response to therapy.

Murray(M M),Mullan(P B),Harkin(D P) Biochem Soc Trans 2008-02-05

...BRCA1 in transcriptional regulation; BRCA1 has been shown to interact with the Pol II holoenzyme complex and to interact...

Cancer risk reduction and reproductive concerns in female BRCA1/2 mutation carr…

Staton(Ashley D),Kurian(Allison W),Cobb(Kris… Fam Cancer 2008-10-09

...BRCA1/2 mutations (13%).,Although they expressed substantial concern about transmitting BRCA1/2 mutations to their child...

MDM2 SNP309 accelerates breast and ovarian carcinogenesis in BRCA1 and BRCA2 ca…

Yarden(Ronit I),Friedman(Eitan),Metsuyanim(S… Breast Cancer Res Treat 2008-11-13

...BRCA1/2 mutation carriers, 120 asymptomatic BRCA1/2 mutation carriers and 187 sporadic breast cancer patients. The frequ...

Brca1 in immunoglobulin gene conversion and somatic hypermutation.

Longerich(Simonne),Orelli(Brian J),Martin(Ri… DNA Repair (Amst) 2008-05-13

...Brca1 confer susceptibility to breast cancer and genomic instability indicative of aberrant repair of DNA breaks. Brca1 ...

Genetic polymorphisms and micronucleus formation: a review of the literature.

Iarmarcovai(G),Bonassi(S),Botta(A),Baan(R A)… Mutat Res 2008-07-31

...BRCA1 and BRCA2 mutations (with or without breast cancer) show enhanced sensitivity to clastogens. Some evidence further...

Identification of BRCA1 missense substitutions that confer partial functional a…

Lovelock(Paul K),Spurdle(Amanda B),Mok(Myth … Breast Cancer Res 2008-03-06

Many of the DNA sequence variants identified in the breast cancer susceptibility gene BRCA1 remain unclassified in terms...

[Molecular genetics and clinics of hereditary breast cancer].

Schmutzler(R K) Verh Dtsch Ges Pathol 2008-01-25

...BRCA1 and BRCA2, have been identified and account for a risk of up to 80% for breast cancer and up to 40% for ovarian ca...

[Molecular carcinogenesis of ovarian carcinoma].

Diebold(J) Verh Dtsch Ges Pathol 2008-01-25

...BRCA1/2 and TP53 mutations. The pattern of molecular aberrations of carcinosarcomas (Malignant müllerian mixed tumours) ...

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