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TP53 BRCA1 CRISPR single-cell cancer

Lo(Shaw-Hwa),Chernoff(Herman),Cong(Lei),Ding… Proc Natl Acad Sci U S A 2008-10-24

...BRCA1 plays a dominant and central role. The apparent interactions of BRCA1 with many other genes suggests the conjectur...

Li(Huan),Lau(Choiwan),Lu(Jianzhong) Analyst 2008-12-05

...BRCA1) and showed high selectivity and attomolar-femtomolar sensitivity. The mixture of three different capture probe co...

Shaaban(Abeer M),Green(Andrew R),Karthik(Suc… Clin Cancer Res 2008-09-30

...BRCA1; and correlated inversely with metastasis and vascular invasion. Tumors coexpressing ERbeta2 and ERalpha had bette...

Tommasi(Stefania),Pilato(Brunella),Pinto(Ros… Mutat Res 2008-11-12

...BRCA1 and one BRCA2 intronic variants able to determine alternative splicing. Furthermore, Q356R BRCA1 and N289H BRCA2 a...

Rochefort(Henri),Rouëssé(Jacques), Bull Acad Natl Med 2008-10-16

...BRCA1/2 genes). Most of the increase is due to sporadic cases associated with hormonal, reproductive and nutritional fac...

Oldenburg(Rogier A),Kroeze-Jansema(Karin H G… Genes Chromosomes Cancer 2008-12-08

...BRCA1 and BRCA2 explain only 20-25% of this risk, suggesting the existence of other breast cancer susceptibility genes. ...

Kuznetsov(Sergey G),Liu(Pentao),Sharan(Shyam… Nat Med 2008-08-21

Individuals with mutations in breast cancer susceptibility genes BRCA1 and BRCA2 have up to an 80% risk of developing br...

Sordet(Olivier),Larochelle(Stéphane),Nicolas… J Mol Biol 2008-11-03

...Brca1 dependent, suggesting a role for Brca1 in the repair or removal of transcription-blocking Top1-DNA cleavage comple...

Han(Pei),Li(Qing),Zhu(Yu-Xian) Plant Cell 2008-12-10

...BRCA1-associated RING domain 1), which had previously been implicated in DNA repair functions; we find that it also regu...

Ashworth(Alan) J Clin Oncol 2008-08-14

...BRCA1 and BRCA2, are highly sensitive to blockade of the repair of DNA single-strand breaks via the inhibition of the en...

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