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How do real tumors become resistant to cisplatin?

Borst(Piet),Rottenberg(Sven),Jonkers(Jos) Cell Cycle 2008-09-15

...Brca1 gene do not become resistant to cisplatin ever, although they invariably become resistant to a variety of other an...

Screening BRCA1 and BRCA2 unclassified variants for splicing mutations using re…

Bonnet(C),Krieger(S),Vezain(M),Rousselin(A),… J Med Genet 2008-09-18

Many unclassified variants (UV) of BRCA1 or BRCA2 may have an effect on pre-mRNA splicing. Patient blood samples suitabl...

Gene expression profiling of breast cells induced by X-rays and heavy ions.

Roy(D),Guida(P),Zhou(G),Echiburu-Chau(C),Cal… Int J Mol Med 2008-07-08

...BRCA1, BIRC2/CIAP1, CENP-E, DDB1, MRE11A, RAD54/ATRX, Wip1 and XPF/ERCC4. A number of candidate genes reported here may ...

Histopathological findings and follow-up after prophylactic mastectomy and imme…

Isern(A E),Loman(N),Malina(J),Olsson(H),Ring… Eur J Surg Oncol 2008-10-02

...BRCA1 or BRCA2 mutation carriers. All breast specimens have been examined histopathologically according to a prospective...

Association of common ATM variants with familial breast cancer in a South Ameri…

González-Hormazábal(Patricio),Bravo(Teresa),… BMC Cancer 2008-10-09

...BRCA1/2 negatives and 11 BRCA1/2 positives. We further perform a case-control study between the subgroup of 126 cases BR...

Secondary BRCA1 mutations in BRCA1-mutated ovarian carcinomas with platinum res…

Swisher(Elizabeth M),Sakai(Wataru),Karlan(Be… Cancer Res 2008-06-10

...BRCA1 also occur in BRCA1-mutated ovarian cancer with platinum resistance. We evaluated nine recurrent BRCA1-mutated ova...

[Nasosinusal adenocarcinoma: molecular and genetic analysis by MLPA].

Llorente(José L),Aldama(Patricia),Alvarez-Ma… Acta Otorrinolaringol Esp 2008-08-07

...BRCA1 significantly correlated with the posterior development of metastases and with worse survival. Also gains of PIK3C...

Receiving inconclusive genetic test results: an interpretive description of the…

Maheu(Christine),Thorne(Sally) Res Nurs Health 2008-12-17

...BRCA1/2 genetic test results. Although these women received similar information on the technical meaning of an inconclus...

The average cumulative risks of breast and ovarian cancer for carriers of mutat…

Milne(Roger L),Osorio(Ana),Cajal(Teresa Ramó… Clin Cancer Res 2008-09-18

It is not clear that the published estimates of the breast and ovarian cancer penetrances of mutations in BRCA1 and BRCA...

BRCA2 gene mutations in Slovenian male breast cancer patients.

Besic(Nikola),Cernivc(Barabara),de Grève(Jac… Genet Test 2008-08-11

...BRCA1 or BRCA2 genes. There is no information available about the frequency of BRCA gene mutations in Slovenian MBC popu...

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