...BRCA1/BRCA2 breast cancer families, targeting the PALB2 region. Also, screening for the 1592delT founder mutation in the...
...BRCA1 and BRCA2, while this attribution is not yet well defined among Africans. To help determine the contribution of BR...
...BRCA1 mutation.,Results suggest that the SPeeDD system is effective at prioritizing candidate deletions and duplications...
...BRCA1, BRCA2, CDKN2A, APC, CDH1) was carried out on 32 BRCA1-associated and 46 sporadic breast carcinomas and on normal ...
...BRCA1/2 mutation families, and might be biased because BRCA1/2 mutations explain only a small proportion of the familial...
...BRCA1, are sequestered at unrepaired DSBs. All four mutants fail to silence the X and Y chromosomes (MSCI failure), whic...
...BRCA1 and BRCA2 in hereditary breast/ovarian cancer, though low in prevalence, are highly penetrant and show geographica...
...BRCA1 and BRCA2 genes confer high risk of breast and ovarian cancer, but account approximately for only 15% of familial ...
...BRCA1-deficient tumors. These data provide an example of a specific and recurrent oncogenic consequence of BRCA1-depende...
...BRCA1 and BRCA2 mutation-positive breast cancers wherein those with BRCA1 mutations are frequently estrogen receptor (ER...
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