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Cyclin D1 expression analysis in familial breast cancers may discriminate BRCAX…

Colombo(Mara),Giarola(Monica),Mariani(Luigi)… Mod Pathol 2008-11-13

Most familial breast cancers arise in patients who tested negative for germline mutations in BRCA1 and BRCA2 genes (also...

Genome-wide association study provides evidence for a breast cancer risk locus …

Gold(Bert),Kirchhoff(Tomas),Stefanov(Stefan)… Proc Natl Acad Sci U S A 2008-04-15

...BRCA1/2 mutation-negative AJ familial cases and 299 cancer-free AJ controls using chi(2) and the Cochran-Armitage trend ...

Age-associated increase in aneuploidy and changes in gene expression in mouse e…

Pan(Hua),Ma(Pengpeng),Zhu(Wenting),Schultz(R… Dev Biol 2008-05-05

...BRCA1 expression is reduced in oocytes obtained from old females and RNAi-mediated reduction of BRCA1 in oocytes obtaine...

Raman multiplexers for alternative gene splicing.

Sun(Lan),Yu(Chenxu),Irudayaraj(Joseph) Anal Chem 2008-05-20

...BRCA1) by surface-enhanced Raman scattering (SERS). A four-plex detection scheme using nonfluorescent labels was demonst...

Family history as a predictor of uptake of cancer preventive procedures by wome…

Metcalfe(K A),Foulkes(W D),Kim-Sing(C),Ainsw… Clin Genet 2008-06-03

...BRCA1 mutation (OR = 0.49, p = 0.0004). Among women with a BRCA1 or BRCA2 mutation, family history predicts the uptake o...

Analysis of GADD45A sequence variations in French Canadian families with high r…

Desjardins(Sylvie),Ouellette(Geneviève),Labr… J Hum Genet 2008-08-13

...BRCA1 represses GADD45A expression through interaction with the zinc finger protein ZNF350. Moreover, BRCA1 can activate...

A prospective study of risk-reducing salpingo-oophorectomy and longitudinal CA-…

Greene(Mark H),Piedmonte(Marion),Alberts(Dav… Cancer Epidemiol Biomarkers P… 2008-06-17

...BRCA1/2 mutations. These data will aid in elucidating the effect of RRSO on breast/ovarian cancer risk and the effects o...

The BOADICEA model of genetic susceptibility to breast and ovarian cancers: upd…

Antoniou(A C),Cunningham(A P),Peto(J),Evans(… Br J Cancer 2008-06-05

...BRCA1 and BRCA2, as well as by the joint multiplicative effects of many genes (polygenic component). We have now updated...

Phenylbutyrate interferes with the Fanconi anemia and BRCA pathway and sensitiz…

Burkitt(Kyunghee),Ljungman(Mats) Mol Cancer 2008-05-23

...BRCA1 protein. Furthermore, we found that cancer cells defective in the FA pathway were also sensitized to cisplatin by ...

A timescale and phylogeny for "bandicoots" (Peramelemorphia: Marsupialia) based…

Meredith(Robert W),Westerman(Michael),Spring… Mol Phylogenet Evol 2008-07-31

...BRCA1, IRBP, Rag1, and vWF). We analyzed this concatenation using maximum parsimony, maximum likelihood, and Bayesian me...

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