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Cell biology of cancer: BRCA1 and sister chromatid pairing reactions?

Skibbens(Robert V) Cell Cycle 2008-06-16

...BRCA1 mutant cells. Linking cohesion to BRCA1-dependent tumorigenesis are reports that BRCA1-associated components (DNA ...

Asymmetric real-time PCR detection of BRCA1 5382insC mutation by melting curve …

Kroupis(Christos),Christopoulos(Kostantinos)… Clin Chim Acta 2008-06-03

5382insC BRCA1 frameshift mutation is a common founder mutation for many populations worldwide and a high-risk allele fo...

BARD1 regulates BRCA1-mediated transactivation of the p21WAF1/CIP1 and Gadd45 p…

Fabbro(Megan),Henderson(Beric R) Cancer Lett 2008-06-24

...BRCA1, but repressed BRCA1-mediated transactivation by up to 75% in transfected cells normalized for nuclear BRCA1 level...

Endocrinology of the wild and mutant BRCA1 gene and types of hormonal carcinoge…

Berstein(Lev M) Future Oncol 2008-02-21

...BRCA1 mutants and knock-downs are unable to inhibit the transcriptional activity of estrogen receptor-alpha, in BRCA1 mu...

Brca1 breast tumors contain distinct CD44+/CD24- and CD133+ cells with cancer s…

Wright(Mollie H),Calcagno(Anna Maria),Salcid… Breast Cancer Res 2008-06-11

Whether cancer stem cells occur in BRCA1-associated breast cancer and contribute to therapeutic response is not known.,W...

Upregulated ATM gene expression and activated DNA crosslink-induced damage resp…

Yamamoto(Kazuhiko),Nihrane(Abdallah),Aglipay… Mol Med 2008-05-27

...BRCA1 or BRCA2. Precancerous lesions are believed to trigger the DNA damage response (DDR), and we focused on the DDR in...

Bisulphite differential denaturation PCR for analysis of DNA methylation.

Rand(Keith N),Mitchell(Susan M),Clark(Susan … Epigenetics 2008-01-15

...BRCA1 and MAGE-A1, is demonstrated with selectivity observed at a ratio of down to one unmethylated molecule in 10(5) me...

Damage-induced ubiquitylation of human RNA polymerase II by the ubiquitin ligas…

Anindya(Roy),Aygün(Ozan),Svejstrup(Jesper Q) Mol Cell 2008-01-22

...BRCA1 were implicated in the process. Surprisingly, using a recently developed assay system, we found that these factors...

What makes tumors multidrug resistant?

Borst(Piet),Jonkers(Jos),Rottenberg(Sven) Cell Cycle 2008-03-25

...Brca1 and p53. These tumors respond to monotherapy with the maximal tolerable dose of doxorubicin, or docetaxel, but eve...

Induction and processing of complex DNA damage in human breast cancer cells MCF…

Francisco(Dave C),Peddi(Prakash),Hair(Jessic… Free Radic Biol Med 2008-03-06

...BRCA1 expression.

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