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Critical molecular abnormalities in high-grade serous carcinoma of the ovary.

Köbel(Martin),Huntsman(David),Gilks(C Blake) Expert Rev Mol Med 2008-09-03

...BRCA1/2, TP53 and RB1/CCND1/CDKN2A/E2F) found in high-grade serous carcinomas of the ovary, which account for most ovari...

MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand …

Wu(Liming),Luo(Kuntian),Lou(Zhenkun),Chen(Ju… Proc Natl Acad Sci U S A 2008-09-16

...BRCA1 C-terminal (BRCT) domains of NBS1. Disruption of the MDC1-NBS1 interaction results in failure of NBS1 accumulation...

Androgen regulation of the androgen receptor coregulators.

Urbanucci(Alfonso),Waltering(Kati K),Suikki(… BMC Cancer 2008-11-18

...BRCA1, beta-catenin, AIB3, AIB1, CBP, STAT1, NCoR1, AES, cyclin D1, p300, ARA24, LSD1, BAG1L, gelsolin, prohibitin, JMJD...

A functional polymorphism in the miR-146a gene and age of familial breast/ovari…

Shen(Jie),Ambrosone(Christine B),DiCioccio(R… Carcinogenesis 2008-10-14

...BRCA1 and BRCA2, which are key breast and ovarian cancer genes. To examine whether rs2910164 plays any role in breast an...

Power spectral analysis of mammographic parenchymal patterns for breast cancer …

Li(Hui),Giger(Maryellen L),Olopade(Olufunmil… J Digit Imaging 2008-10-21

...BRCA1/BRCA2 gene mutation and 142 low-risk women) were retrospectively collected and digitized. Because age is a very im...

[Basal-like carcinoma of the breast--the actual review and clinico-pathological…

Kinkor(Z) Ceska Gynekol 2008-04-01

...BRCA1 mutated familial cancer. Existence of the rare noninvasive in situ phase of the basal-like carcinoma having simila...

Breast cancers detected with imaging screening in the BRCA population: emphasis…

Causer(Petrina A),Jong(Roberta A),Warner(Ell… Radiographics 2008-04-02

...BRCA1 or BRCA2 gene, has been established in numerous studies and is now becoming part of routine clinical practice. Des...

Variation of breast cancer risk among BRCA1/2 carriers.

Begg(Colin B),Haile(Robert W),Borg(Ake),Malo… JAMA 2008-01-15

The risk of breast cancer in BRCA1 and BRCA2 mutation carriers has been examined in many studies, but relatively little ...

Prostate cancer in male BRCA1 and BRCA2 mutation carriers has a more aggressive…

Mitra(A),Fisher(C),Foster(C S),Jameson(C),Ba… Br J Cancer 2008-03-27

...BRCA1 and BRCA2 mutation carriers with PRCA. The archived histopathological tissue sections of 20 BRCA1/2 mutation carri...

BRCA1-mediated ubiquitination inhibits topoisomerase II alpha activity in respo…

Shinagawa(Hirokuni),Miki(Yoshio),Yoshida(Kiy… Antioxid Redox Signal 2008-05-19

...BRCA1, a tumor-suppressor gene, appeared to be involved in these alterations in topoisomerase IIalpha. Furthermore, the ...

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