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TP53 BRCA1 CRISPR single-cell cancer

Mahadevaiah(Shantha K),Bourc'his(Déborah),de… J Cell Biol 2008-08-26

...BRCA1, are sequestered at unrepaired DSBs. All four mutants fail to silence the X and Y chromosomes (MSCI failure), whic...

Oldenburg(Rogier A),Kroeze-Jansema(Karin H G… Genes Chromosomes Cancer 2008-12-08

...BRCA1 and BRCA2 explain only 20-25% of this risk, suggesting the existence of other breast cancer susceptibility genes. ...

Rochefort(Henri),Rouëssé(Jacques), Bull Acad Natl Med 2008-10-16

...BRCA1/2 genes). Most of the increase is due to sporadic cases associated with hormonal, reproductive and nutritional fac...

Tommasi(Stefania),Pilato(Brunella),Pinto(Ros… Mutat Res 2008-11-12

...BRCA1 and one BRCA2 intronic variants able to determine alternative splicing. Furthermore, Q356R BRCA1 and N289H BRCA2 a...

Urbanucci(Alfonso),Waltering(Kati K),Suikki(… BMC Cancer 2008-11-18

...BRCA1, beta-catenin, AIB3, AIB1, CBP, STAT1, NCoR1, AES, cyclin D1, p300, ARA24, LSD1, BAG1L, gelsolin, prohibitin, JMJD...

Wu(Liming),Luo(Kuntian),Lou(Zhenkun),Chen(Ju… Proc Natl Acad Sci U S A 2008-09-16

...BRCA1 C-terminal (BRCT) domains of NBS1. Disruption of the MDC1-NBS1 interaction results in failure of NBS1 accumulation...

Gunnarsson(Haukur),Arason(Adalgeir),Gillande… J Negat Results Biomed 2008-09-26

...BRCA1/BRCA2 breast cancer families, targeting the PALB2 region. Also, screening for the 1592delT founder mutation in the...

Tan(D S P),Marchiò(C),Reis-Filho(J S) J Clin Pathol 2008-10-21

...BRCA1 and BRCA2, are responsible for about 16% of the familial risk of breast cancer. Even though subsequent studies hav...

Zajac(Magdalena),Moneo(Maria Victoria),Carne… Mol Cancer Ther 2008-10-22

...BRCA1-null (UACC 3199, HCC 1937, and MBA-MD-436) and BRCA1-wt breast cancer cell lines (MCF-7, MBA-MD-157, and Hs578T) t...

Kalb(R),Neveling(K),Nanda(I),Schindler(D),Ho… Genome Dyn 2008-12-18

...BRCA1, BRCA2, and the RAD51 recombinase. Biallelic mutations in BRCA2 cause a severe FA-like phenotype, as do biallelic ...

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