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Clinical utility of diagnostic laparoscopy for ovarian metastasis from breast...

Sato(S),Osakabe(M),Hosomi(S),Kitamura(A),J... Int Cancer Conf J 2026-07-00

...BRCA1 mutation (c.117_118del) and a history of left-sided triple-negative breast cancer, invasive ductal carcinoma, clin...

HELZ is a RNA-DNA helicase that resolves R loops to facilitate homologous rec...

Haji-Seyed-Javadi(R),Koyen(AE),Rath(SK),Wu... Nat Commun 2026-07-23

...BRCA1 recruitment to DSBs by preventing R loop accumulation, thereby promoting DNA end resection and HR to prevent R loo...

Comprehensive BRCA1/2 mutation landscape in prostate cancer in the UAE and Ar...

Al Shareef(ZM),Al-Shahrabi(RM),Bhamidimarr... Front Cell Dev Biol None

...BRCA1 and BRCA2, increase PCa risk, with BRCA2 conferring up to 8.6-fold and BRCA1 a 3.7-fold risk. The objective is to ...

BRCA1/2 Reversion Mutations and Cancer Therapy Resistance.

Qi(W),Yang(G),Zhang(Y),Han(L),Mayo(KH),Zen... Biology (Basel) 2026-05-31

...BRCA1/2, their pathogenic mutation profiles, and therapeutic strategies targeting BRCA1/2-deficient cancers. Despite the...

Deciphering the Pleiotropic Role of ARID1a and RIF1 in Endometrioid Ovarian C...

Kordowitzki(P),Velho(RV),Bock(S),Sehouli(J... Cells 2026-06-04

...BRCA1 exhibited significantly (p = 2.82 × 10-4) lower ARID1a expression levels compared with corresponding wild-type tum...

A zero-parameter first-principles gate framework for full-length TP53 missens...

Iizumi(M) PLoS Comput Biol 2026-06-00

...BRCA1, the same channels capture the dominant pathogenic mechanisms in each protein as a proof of principle, while resid...

Machine Learning-Based Prediction of Breast Cancer in Women: Insights From Fe...

Allahqoli(L),Behzadi(MH),Aghamohammadi(SZ)... Int J Breast Cancer None

...BRCA1/2 mutations and family history), reproductive and hormonal characteristics (age at menarche, menopause, and infert...

From text to translation: using language models to prioritize variants for cl...

Li(W),Li(X),Lavallee(E),Saparov(A),Zitnik(... Genome Med 2026-05-19

...BRCA1 (p = [Formula: see text]), TP53 (p = [Formula: see text]), and PTEN (p = [Formula: see text]) with an AUROC = 0.92...

HRR gene promoter methylation-guided nomogram predicts PARP inhibitor efficac...

Zhou(Z),Ge(B),Chen(T),Shen(S),Tu(N),Shen(Y... Clin Epigenetics 2026-05-19

...BRCA1(2S)_Pos2, BRCA2(1S)_Pos1, BRCA2(1S)_Pos7, and RAD51D_Pos6-were identified as independent predictors of PARPi sensi...

High-Grade Serous Ovarian Carcinoma Presenting as Cardiac Tamponade.

Zhang(DT),Hanna(K),Wu(M),Rahman(T) JACC Case Rep 2026-07-01

...BRCA1), B7-H4 positive, high-grade serous ovarian carcinoma with metastasis to the lungs presented with subacute dyspnea...

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