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TP53 BRCA1 CRISPR single-cell cancer

Kaas(R),Rutgers(E J Th) Ned Tijdschr Geneeskd 2008-12-18

...BRCA1 gene mutation, in whom a high percentage of rapidly proliferating grade III carcinomas are found.

Sugano(Kokichi),Nakamura(Seigo),Ando(Jiro),T… Cancer Sci 2008-12-17

...BRCA1/2 gene showed 28 types of deleterious mutations in 36 subjects (26.7%), including 13 types of BRCA1 mutations in 1...

Drew(Yvette),Calvert(Hilary) Ann N Y Acad Sci 2008-10-28

...BRCA1/2 mutations are responsible for the majority of genetic breast/ovarian cancers, known as the hereditary breast ova...

Wang(Rui-Hong),Zheng(Yin),Kim(Hyun-Seok),Xu(… Mol Cell 2008-11-12

...BRCA1 predispose women to breast and ovarian cancers. However, the downstream mediators of BRCA1 function in tumor suppr...

Chisholm(Karen M),Goff(Barbara A),Garcia(Roc… Cancer Genet Cytogenet 2008-06-24

...BRCA1 mutations. Normal and tumor DNA from 14 ovarian tumors associated with inherited BRCA1 mutations were extracted an...

Bonnet(C),Krieger(S),Vezain(M),Rousselin(A),… J Med Genet 2008-09-18

Many unclassified variants (UV) of BRCA1 or BRCA2 may have an effect on pre-mRNA splicing. Patient blood samples suitabl...

Roy(D),Guida(P),Zhou(G),Echiburu-Chau(C),Cal… Int J Mol Med 2008-07-08

...BRCA1, BIRC2/CIAP1, CENP-E, DDB1, MRE11A, RAD54/ATRX, Wip1 and XPF/ERCC4. A number of candidate genes reported here may ...

Wicha(Max S) Breast Cancer Res 2008-07-21

...BRCA1 gene involved in hereditary breast cancer plays a role in breast stem cell function. Furthermore, studies using mo...

Willems(Amber J),Dawson(Sarah-Jane),Samaratu… Clin Cancer Res 2008-08-18

...BRCA1 and BRCA2 mutation, respectively. We examined LOH at the BRCA1 and BRCA2 genes using multiplex ligation-dependent ...

Llorente(José L),Aldama(Patricia),Alvarez-Ma… Acta Otorrinolaringol Esp 2008-08-07

...BRCA1 significantly correlated with the posterior development of metastases and with worse survival. Also gains of PIK3C...

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