...BRCA1.,We show that AhR, a transcription factor, can bind specifically to AD1 in the C-terminal region of BRCA1 and affe...
...BRCA1/gammaH2AX/RNA polymerase II) of meiotic chromosomes in an azoospermic carrier of a t(8;13) reciprocal translocatio...
...BRCA1), (5) apoptosis (p53, Bcl-2, thioredoxin), and (6) cell proliferation (MIB-1, nuclear grade). In addition, recentl...
We investigated the uptake of genetic testing by 54 families in South East Scotland with a BRCA1/2 mutation. At a median...
...BRCA1 missense variant M1775K is pathogenic. Functional assays in yeast and mammalian cells showed that the BRCA1 BRCT d...
...BRCA1/2 genetic testing with their children, especially adolescent children. What is less known is the extent to which t...
...BRCA1 and BRCA2. A total of 166 mutations were identified 110 (25%) in BRCA1 and 56 (13%) in BRCA2. In families without ...
...BRCA1 or 2), but most of the time it remains unknown. However, all women considered at high risk, because of their famil...
...BRCA1/2 mutation status. A complete analysis of the BRCA1/2 coding regions was performed on the 217 women from high-risk...
...BRCA1/BRCA2.,We sequenced BRCA1/BRCA2 in 1,469 population-based female breast cancer patients diagnosed between the ages...
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