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BRCA1 and BRCA2 missense variants of high and low clinical significance influen…

Waddell(Nic),Ten Haaf(Anette),Marsh(Anna),Jo… PLoS Genet 2008-06-19

...BRCA1 carriers, 22 BRCA2 carriers, and 27 BRCAX individuals. A subset of 10 BRCAX individuals carried rare BRCA1/2 seque...

Analysis of selected genes in neuroendocrine tumours: insulinomas and phaeochro…

Hrasćan(R),Pećina-Slaus(N),Martić(T Nikuseva… J Neuroendocrinol 2008-12-09

...BRCA1, nm23-H1, SDHB and SDHD for loss of heterozygosity (LOH). Twenty-two sporadic insulinomas and 15 phaeochromocytoma...

BRCT domains: phosphopeptide binding and signaling modules.

Rodriguez(Maria C),Songyang(Zhou) Front Biosci 2008-09-19

...BRCA1 C-terminus (BRCT) domains are essential for the tumor suppressor function of BRCA1, and have been found in a varie...

Promoter methylation of cancer-related genes in gastric carcinoma.

Poplawski(T),Tomaszewska(K),Galicki(M),Moraw… Exp Oncol 2008-09-03

...BRCA1, hMLH1, Fas in gastric cancer patients.,The methylation pattern of the genes was assessed by methylation specific ...

A review of the clinical relevance of mismatch-repair deficiency in ovarian can…

Pal(Tuya),Permuth-Wey(Jenny),Sellers(Thomas … Cancer 2008-09-08

...BRCA1 and BRCA2 mutations. An epigenetic mechanism known to cause inactivation of the MMR system is promoter hypermethyl...

Genetic predisposition to breast cancer: past, present, and future.

Turnbull(Clare),Rahman(Nazneen) Annu Rev Genomics Hum Genet 2008-12-04

...BRCA1 and BRCA2 are high-penetrance breast cancer predisposition genes identified by genome-wide linkage analysis and po...

The molecular pathology of hereditary breast cancer.

Palacios(J),Robles-Frías(M J),Castilla(M A),… Pathobiology 2008-07-22

...BRCA1 and BRCA2 genes differs from sporadic breast cancer and from non-BRCA1/2 familial breast carcinomas. Most BRCA1 ca...

Clinical significance of promoter hypermethylation of RASSF1A, RARbeta2, BRCA1 …

Bagadi(Sarangadhara Appala Raju),Prasad(Chan… Life Sci 2008-08-28

...BRCA1 and HOXA5, in 54 breast cancers and 5 distant normal breast tissues of Indian patients. The methylation data were ...

Forkhead-box A1 (FOXA1) expression in breast cancer and its prognostic signific…

Habashy(Hany Onsy),Powe(Desmond G),Rakha(Ema… Eur J Cancer 2008-12-02

...BRCA1 and E-cadherin. Its expression showed an inverse relation with basal CKs (CK14 and CK5/6) and P-cadherin. We found...

Xenografts of primary human gynecological tumors grown under the renal capsule …

Press(Joshua Z),Kenyon(Jennifer A),Xue(Hui),… Gynecol Oncol 2008-08-05

...BRCA1 germline mutation carriers were analyzed for histopathologic response (tumor volume, apoptotic and mitotic indices...

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