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Intrinsic disorder in scaffold proteins: getting more from less.

Cortese(Marc S),Uversky(Vladimir N),Dunker(A… Prog Biophys Mol Biol 2008-11-13

...BRCA1, GSK-3beta, p53, Ste5, titin, Fus3, BRCA1, MAP2, D-AKAP2 and AKAP250. Among the mechanisms discussed are: molecula...

Application of multiplex PCR with histopathologic features for detection of fam…

Rassi(H),Houshmand(M),Hashemi(M),Majidzadeh(… Tsitol Genet 2008-08-08

...BRCA1 and BRCA2 genes are associated with a greatly increased risk for development of familial breast cancer. Frequency ...

A novel breast cancer-associated BRIP1 (FANCJ/BACH1) germ-line mutation impairs…

De Nicolo(Arcangela),Tancredi(Mariella),Lomb… Clin Cancer Res 2008-09-16

BRCA1-interacting protein 1 (BRIP1; FANCJ/BACH1), which encodes a DNA helicase that interacts with BRCA1, has been sugge...

The 3020insC NOD2 gene mutation in patients with ovarian cancer.

Magnowski(Piotr),Medrek(Krzysztof),Magnowska… Ginekol Pol 2008-11-18

...BRCA1 and BRCA2 genes are responsible for an increased risk of ovarian cancer. The role of mutations in NOD2 gene in thi...

Clinically applicable models to characterize BRCA1 and BRCA2 variants of uncert…

Spearman(Andrew D),Sweet(Kevin),Zhou(Xiao-Pi… J Clin Oncol 2008-12-24

...BRCA1 or BRCA2 mutations. Study participants included individuals with known deleterious mutations in BRCA1 or BRCA2 and...

International registries of families at high risk of pancreatic cancer.

Greenhalf(William),Malats(Nuria),Nilsson(Mag… Pancreatology 2008-12-17

...BRCA1/2 mutations with a family history of pancreatic cancer and kindred with multiple pancreatic cancers were considere...

BRCA mutation-negative women from hereditary breast and ovarian cancer families…

Bakos(Alexis D),Hutson(Sadie P),Loud(Jennife… Health Expect 2008-11-10

When women from families with a known BRCA1 or BRCA2 mutation test negative for the family mutation, it is assumed that ...

Reprimo as a potential biomarker for early detection in gastric cancer.

Bernal(Carolina),Aguayo(Francisco),Villarroe… Clin Cancer Res 2008-11-26

...BRCA1, p73, RARbeta, hMLH1, RIZI, RUNX3, MGMT, and TIMP3) were statistically associated with a particular variant of gas...

Role of CHK2 in cancer development.

Perona(Rosario),Moncho-Amor(Verónica),Machad… Clin Transl Oncol 2008-11-18

...BRCA1 and E2F1. A role of Chk2 as a candidate tumour suppressor has been suggested based on both mouse genetics and soma...

Impaired tamoxifen metabolism reduces survival in familial breast cancer patien…

Newman(William G),Hadfield(Kristen D),Latif(… Clin Cancer Res 2008-10-08

...BRCA1, 68 BRCA2) with familial breast cancer who had been treated with 20-mg tamoxifen following surgery.,Eight (7%) ind...

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