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TP53 BRCA1 CRISPR single-cell cancer

Kauff(Noah D),Domchek(Susan M),Friebel(Tara … J Clin Oncol 2008-04-08

...BRCA1 mutation carriers.,A total of 1,079 women 30 years of age and older with ovaries in situ and a deleterious BRCA1 o...

Friebel(Tara M),Domchek(Susan M),Neuhausen(S… Clin Breast Cancer 2008-03-06

...BRCA1 or BRCA2 (BRCA1/2) mutations can reduce cancer incidence and mortality by using bilateral prophylactic oophorectom...

Ferguson(Kyle A),Chow(Victor),Ma(Sai) Hum Reprod 2008-05-27

...BRCA1/gammaH2AX/RNA polymerase II) of meiotic chromosomes in an azoospermic carrier of a t(8;13) reciprocal translocatio...

Boukovinas(Ioannis),Papadaki(Chara),Mendez(P… PLoS One 2008-12-12

...BRCA1 mRNA levels were assessed by quantitative PCR and correlated with response, time to progression and survival. As B...

Sato(Ko),Rajendra(Eeson),Ohta(Tomohiko) BMC Biochem 2008-12-12

...BRCA1 pathways. To gain further improvements in breast cancer survival, new types of drugs might be required, and small ...

Sugano(Kokichi),Nakamura(Seigo),Ando(Jiro),T… Cancer Sci 2008-12-17

...BRCA1/2 gene showed 28 types of deleterious mutations in 36 subjects (26.7%), including 13 types of BRCA1 mutations in 1...

Newman(William G),Hadfield(Kristen D),Latif(… Clin Cancer Res 2008-10-08

...BRCA1, 68 BRCA2) with familial breast cancer who had been treated with 20-mg tamoxifen following surgery.,Eight (7%) ind...

Beran(Tammy M),Stanton(Annette L),Kwan(Lorna… Ann Behav Med 2008-11-24

...BRCA1/2- (96 uninformative negative and 21 true negative) and 38 were BRCA1/2+. Linear mixed model analyses revealed a c...

Kaas(R),Rutgers(E J Th) Ned Tijdschr Geneeskd 2008-12-18

...BRCA1 gene mutation, in whom a high percentage of rapidly proliferating grade III carcinomas are found.

Rottenberg(Sven),Jaspers(Janneke E),Kersberg… Proc Natl Acad Sci U S A 2008-12-22

...BRCA1 dysfunction. The DNA-repair defects characteristic of BRCA1-deficient cells confer sensitivity to poly(ADP-ribose)...

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