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The role of early life genistein exposures in modifying breast cancer risk.

Warri(A),Saarinen(N M),Makela(S),Hilakivi-Cl… Br J Cancer 2008-05-27

...BRCA1 and PTEN. It will be debated whether mammary stem cells are the targets of genistein-induced alterations and also ...

A novel domain of BRCA1 interacts with p53 in breast cancer cells.

Buck(Martina) Cancer Lett 2008-10-14

...BRCA1 (amino acids 224-500) and the second BRCT domain of the BRCA1 C-terminus may interact with p53, quantitative bioph...

Characterization of three new serous epithelial ovarian cancer cell lines.

Ouellet(Véronique),Zietarska(Magdalena),Port… BMC Cancer 2008-07-22

...BRCA1/2 mutations found to recur in the French Canadian population. Conventional cytogenetics and spectral karyotype (SK...

Structure-guided mutational analysis of the OB, HhH, and BRCT domains of Escher…

Wang(Li Kai),Nair(Pravin A),Shuman(Stewart) J Biol Chem 2008-10-06

...BRCA1-like C-terminal) domains. The OB and HhH domains contribute prominently to the protein clamp formed by LigA around...

Ethical issues related to BRCA gene testing in orthodox Jewish women.

Mor(Pnina),Oberle(Kathleen) Nurs Ethics 2008-09-24

...BRCA1 and BRCA2, have a greatly increased risk of developing breast and/or ovarian cancer. The incidence of BRCA gene mu...

RAP80 responds to DNA damage induced by both ionizing radiation and UV irradiat…

Yan(Jun),Yang(Xiao-Ping),Kim(Yong-Sik),Jette… Cancer Res 2008-08-15

...BRCA1) and to translocate to ionizing radiation-induced foci (IRIF). In this study, we show that the BRCT mutant of BRCA...

Inherited cancer predisposition syndromes in Greece.

Apessos(Angela),Papadopoulou(Eirini),Belogia… Anticancer Res 2008-06-05

...BRCA1 and BRCA2), and the rearranged during transfection protooncogene RET which is responsible for multiple endocrine n...

Crystal structure of the BARD1 ankyrin repeat domain and its functional consequ…

Fox(David),Le Trong(Isolde),Rajagopal(Ponni)… J Biol Chem 2008-09-08

...BRCA1. Together, they form a heterodimeric complex responsible for maintaining genomic stability through nuclear functio...

Therapeutic exploitation of tumor cell defects in homologous recombination.

Powell(Simon N),Kachnic(Lisa A) Anticancer Agents Med Chem 2008-06-23

In the decade since the BRCA1 and BRCA2 genes were cloned, much has been learned about the function of these two major c...

[Information spreading about hereditary carriage of a BRCA1/2 mutation and ovar…

Christophe(Véronique),Leroy(Tanguy),Adenis(C… Bull Cancer 2008-06-06

...BRCA1 or BRCA2 mutation. In our country, the information given to the relatives is inevitably mediated by the persons wh...

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