...BRCA1, BRCA2, MSH2, MLH1, TP53, and CDKN2A to illustrate the progress and remaining challenges in this field. We recomme...
...BRCA1, BRCA2, or in one of the mismatch repair (MMR) genes, MLH1, MSH2, or MSH6, to infer pathogenicity.
...BRCA1, BRCA2, CDKN2A, and mismatch repair [MMR] genes MLH1, MSH2, MSH6, and PMS2) and present a detailed review of the i...
...BRCA1 and BRCA2 are among the most resequenced of all genes, and clinical mutation screening of these genes provides an ...
...BRCA1 and BRCA2 account for less than 20% of the genetic risk of breast cancer. The more common sporadic form of breast ...
...BRCA1 predispose women to breast and ovarian cancers. However, the downstream mediators of BRCA1 function in tumor suppr...
...BRCA1, CHEK1, and RAD51). Addition of fludarabine further potentiated DNA damage, which was incompatible with cell survi...
...BRCA1 while the BARD1 C-terminal ankyrin and tandem BRCT repeat domains bind CstF-50 to modulate mRNA processing and RNA...
...BRCA1 tumor-suppressor gene, little is known concerning the mechanisms that cause basal breast cancer or the mechanisms ...
...BRCA1-deficient breast cancer cell lines. Compound 47 is currently undergoing clinical development for the treatment of ...
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