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BRCA1 genetic testing in 106 breast and ovarian cancer families from Southern I…

Russo(Antonio),Calò(Valentina),Agnese(Valent… Breast Cancer Res Treat 2008-01-09

...BRCA1 gene by automatic direct sequencing.,Germline BRCA1 mutations were found in 17 of 106 (16%) Sicilian families. The...

Direct and nondestructive verification of PNA immobilization using click chemis…

Lim(Seong Yoon),Chung(Won-Young),Lee(Hyeon K… Biochem Biophys Res Commun 2008-11-13

...BRCA1.

Five recurrent BRCA1/2 mutations are responsible for cancer predisposition in t…

Krajc(Mateja),Teugels(Erik),Zgajnar(Janez),G… BMC Med Genet 2008-09-26

...BRCA1/2 mutation was found in 56 (39%). Two novel large deletions covering consecutive exons of BRCA1 were found. Five h...

BRCA1/2 in high-risk African American women with breast cancer: providing genet…

Pal(Tuya),Vadaparampil(Susan),Betts(Judy),Mi… Genet Test 2008-12-11

...BRCA1 and BRCA2 (BRCA1/2) in a sample of African American women, recruited through a variety of methods.,We conducted a ...

BRCA mutation-negative women from hereditary breast and ovarian cancer families…

Bakos(Alexis D),Hutson(Sadie P),Loud(Jennife… Health Expect 2008-11-10

When women from families with a known BRCA1 or BRCA2 mutation test negative for the family mutation, it is assumed that ...

Hormone therapy and the risk of breast cancer in BRCA1 mutation carriers.

Eisen(Andrea),Lubinski(Jan),Gronwald(Jacek),… J Natl Cancer Inst 2008-10-22

...BRCA1 because they face a high lifetime risk of breast cancer and because many of these women take HT after undergoing p...

Checking out the centrosome.

Krämer(Alwin),Lukas(Jiri),Bartek(Jiri) Cell Cycle 2007-08-07

...Brca1, Chk1, Chk2, TopBP1, Aurora-A, Plk1, cyclin B1, and Cdk1. However, only very few direct links between their locali...

Brca1-deficient murine mammary epithelial cells have increased sensitivity to C…

Sgagias(Magdalene K),Wagner(Kay-Uwe),Hamik(B… Cell Cycle 2007-08-07

...Brca1(++) and Brca1(-/-) murine mammary epithelial cells (MMECs). These cells were isolated from Brca1 conditional knock...

Breast cancer gene discovery.

Polyak(Kornelia) Expert Rev Mol Med 2007-10-17

...BRCA1 and BRCA2--have been identified. However, germline mutations in these two genes are responsible for only a minorit...

Triple negative breast carcinoma and the basal phenotype: from expression profi…

Diaz(Leslie K),Cryns(Vincent L),Symmans(W Fr… Adv Anat Pathol 2007-12-20

...BRCA1 mutations. For patients with sporadic TNBCs and BP tumors, BRCA1 dysfunction seems to play a major role in the dev...

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