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TP53 BRCA1 CRISPR single-cell cancer

Tai(Yu Chuan),Domchek(Susan),Parmigiani(Giov… J Natl Cancer Inst 2007-12-13

...BRCA1 mutation carriers. The estimated cumulative risk of breast carcinoma for male BRCA1 mutation carriers at age 70 ye...

Martin(Richard W),Orelli(Brian J),Yamazoe(Mi… Cancer Res 2007-12-12

...BRCA1-deficient tumorigenesis remain unclear. Given that BRCA1 is required for cell proliferation, suppressor mutations ...

Fostira(Florentia),Thodi(Georgia),Konstantop… J BUON 2007-11-21

...BRCA1 and BRCA2 genes.

Lubinski(Jan),Korzen(Marcin),Gorski(Bohdan),… J BUON 2007-11-21

In 1999 it has been recognized that 3 BRCA1 abnormalities - 5382insC, C61G and 4153delA - constitute almost 90% of all g...

Ejlertsen(Bent),Gerdes(Anne-Marie A) Ugeskr Laeger 2007-10-30

...BRCA1/2 mutations. The selection of loco-regional therapies might change according to BRCA1/2 mutation status. In order ...

Scata(Kimberly A),El-Deiry(Wafik S) Adv Exp Med Biol 2007-12-14

...BRCA1 for signaling tumor suppression involve some cross-talk including repression of BRCA1 transcription by p53 and alt...

Antoniou(Antonis C),Sinilnikova(Olga M),Sima… Am J Hum Genet 2007-12-13

RAD51 is an important component of double-stranded DNA-repair mechanisms that interacts with both BRCA1 and BRCA2. A sin...

Treszezamsky(Alejandro D),Kachnic(Lisa A),Fe… Cancer Res 2007-09-11

The function of BRCA1 and BRCA2 in DNA repair could affect the sensitivity of cells to cytotoxic agents, and would there...

Zhang(Zhihong),Singh(Meenakshi),Davidson(Sus… Mod Pathol 2007-12-18

...BRCA1 or BRCA2 mutation (we called BRCA1/2 mutation) are known to predispose to the development of ovarian cancer; howev...

Muti(Paola),Rogan(Eleanor),Cavalieri(Ercole) Nutr Cancer 2007-06-25

...BRCA1 and BRCA2 susceptibility genes, familial history of breast cancer, age, higher socioeconomic status, ionizing radi...

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