Alterations in the highly penetrant cancer susceptibility gene BRCA1 are responsible for the majority of hereditary brea...
BRCA1 is a tumor suppressor involved in the maintenance of genome integrity. BRCA1 co-localizes with DNA repair proteins...
...BRCA1 interacting genes BRIP1 and ZNF350), non-homologous end-joining (NHEJ) DNA repair (XRCC4) and homologous recombina...
There is conflicting evidence as to whether individuals who are heterozygous for germ-line BRCA1 or BRCA2 mutations have...
...BRCA1) germline mutation and expression of the human epidermal growth factor receptor 2 (Her2/neu) proto-oncogene seem t...
...BRCA1, as part of a heterodimer with BARD1 (BRCA1-associated RING domain 1), is critical for its role as a tumor suppres...
...BRCA1 and BRCA2, respectively. In the remaining 26 men, we screened for large genomic rearrangements in BRCA1 and BRCA2 ...
...BRCA1, ERalpha and PRB was determined in invasive ductal carcinoma of breast and paired serum DNA. Of the 50 breast canc...
...BRCA1 (an enhancer of AhR-mediated transactivation in breast cancer cells) was significantly decreased and this contribu...
...BRCA1 is familial breast cancer susceptibility gene. Recently, decreased BRCA1 mRNA and protein expression has been iden...
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