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Systemic immune activation in hereditary cancer predisposition syndromes: a c...

Kelemen(I),Horti-Oravecz(K),Bozsik(A),Pócz... BMC Med 2026-08-25

...BRCA1 (gpath(BRCA1)) and in patients living with Lynch syndrome (LS). Pre-cancer women with gpath(BRCA1) exhibited an ac...

Evaluating global clinical trials and development trends of antibody-drug con...

Hu(J),Lai(C),Wang(J),Yan(Z),Yuan(Z),Deng(C... Biomark Res 2026-08-28

...BRCA1, and TP53 were frequently recorded across trial-design and outcome-related fields. Future research should focus on...

Rewired DDR-TGF-β-β-catenin-PD-L1 axis accelerates progression and shapes the...

Liu(W),Chen(S),Wang(L),Xiang(H),Tao(S) Front Immunol None

...BRCA1/RAD51 to replication foci to support viral replication without significantly compromising host HR repair. Upon vir...

BRCA1-derived peptide constructs exhibit sequence-dependent features compatib...

Pektaş(S) Mol Biol Rep 2026-08-06

...BRCA1-derived peptide constructs were used to investigate how hydrophobic motif composition and sequence context influen...

BAP1 Loss in Pleural Mesothelioma Is Associated With Reduced Soluble CCL2 in ...

Nash(A),Rouse(E),Firth(T),Dick(IM),Fear(VS... JTO Clin Res Rep 2026-10-00

...BRCA1-associated protein 1 (BAP1), a multifunctional tumour suppressor protein. Here, we aim to elucidate the effect of ...

Case Report: Spindle cell metaplastic breast carcinoma.

Liu(Y),Sun(X),Liu(J) Front Oncol 2026-00-00

...BRCA1/2 testing showed no detectable mutation. After six cycles of albumin-bound paclitaxel plus carboplatin, ultrasound...

Brca1 heterozygosity leads to hepatic steatosis in male and female mice despi...

Palikhe(S),Qiao(L),Kutz(C),Liang(X),Dhoraj... Metabolism 2026-09-02

...BRCA1 mutation increases the risk of several cancers, including breast and ovarian cancer. While BRCA1 is best known for...

Integrative proteomics reveals MSH6 to modulate PARP inhibitor sensitivity in...

Deng(O),Nepomuceno(TDC),Fang(B),Welsh(EA),... PLoS One 2026-00-00

...BRCA1/2 are well-established biomarkers that predict sensitivity to poly(ADP-ribose) polymerase inhibitors (PARPis). How...

Clinical and biological characteristics associated with loss-of-heterozygosit...

Blanc-Durand(F),Rouleau(E),Pautier(P),Ngoi... J Gynecol Oncol 2026-01-00

...BRCA1 mutations and TERC amplification whereas LOH-low with low-grade endometrioid, MSI, ARID1A, PIK3CA, CTNNB1, and PTE...

Circulating Tumor DNA in Breast Cancer: A Liquid Biopsy Revolution for Non-In...

Obeagu(EI),Okafor(CJ) Breast Cancer (Auckl) 2026-00-00

...BRCA1/2. ctDNA has demonstrated particular utility in identifying minimal residual disease, monitoring therapeutic respo...

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