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TP53 BRCA1 CRISPR single-cell cancer

Franco(M J),Sciurano(R B),Solari(A J) Chromosome Res 2007-12-14

...BRCA1. The chromatin of the non-synaptic X and Y chromosomes contains gamma-H2AX, first as foci and then as homogeneous ...

Fitzgerald(Latricia D),Bailey(Charvann K),Br… FEBS J 2007-12-18

...BRCA1 mutation, increased synergistically when wild-type BRCA1 was reconstituted in the cells, and downregulation of BRC...

Bhatti(Parveen),Struewing(Jeffery P),Alexand… Int J Cancer 2007-12-20

...BRCA1 D652N (rs4986850), PRKDC IVS15 + 6C > T (rs1231202), PRKDC IVS34 + 39T > C (rs8178097) and PRKDC IVS31 - 634C > A ...

Desjardins(Sylvie),Belleau(Pascal),Labrie(Yv… Int J Cancer 2007-12-20

Our current understanding of breast cancer susceptibility involves mutations in the 2 major genes BRCA1 and BRCA2, found...

Myers(Evan R),Havrilesky(Laura J),Kulasingam… Evid Rep Technol Assess (Full… 2007-10-16

...BRCA1/2]), we added studies published subsequent to the reports. We sought evidence on: (a) the analytic performance of ...

Coster(Gideon),Hayouka(Zvi),Argaman(Liron),S… J Biol Chem 2007-12-13

...BRCA1 C-terminal domains of MDC1 and the C terminus of the Cdc27 (APC3) subunit of the APC/C. It requires the phosphoryl...

Cheung(Lydia W T),Lee(Yiu Fai),Ng(Tuen Wai),… FEBS Lett 2007-11-27

The range of BRCA1/BRCA2 gene mutations is diverse and the mechanism accounting for this heterogeneity is obscure. To ga...

Kauff(Noah D),Barakat(Richard R) J Clin Oncol 2007-07-20

...BRCA1 or BRCA2 are at tremendously increased lifetime risk of both breast and BRCA-associated gynecologic (ovarian, fall...

Liu(Xiaoling),Holstege(Henne),van der Gulden… Proc Natl Acad Sci U S A 2007-08-30

...Brca1 and/or p53 in basal epithelial cells. Somatic loss of both BRCA1 and p53 resulted in the rapid and efficient forma...

Rottenberg(Sven),Nygren(Anders O H),Pajic(Ma… Proc Natl Acad Sci U S A 2007-08-30

...Brca1- and p53-deficient mammary tumors arising in conditional mouse mutants to treatment with doxorubicin, docetaxel, o...

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