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TP53 BRCA1 CRISPR single-cell cancer

Ejlertsen(Bent),Gerdes(Anne-Marie A) Ugeskr Laeger 2007-10-30

...BRCA1/2 mutations. The selection of loco-regional therapies might change according to BRCA1/2 mutation status. In order ...

Tai(Yu Chuan),Domchek(Susan),Parmigiani(Giov… J Natl Cancer Inst 2007-12-13

...BRCA1 mutation carriers. The estimated cumulative risk of breast carcinoma for male BRCA1 mutation carriers at age 70 ye...

Antoniou(Antonis C),Sinilnikova(Olga M),Sima… Am J Hum Genet 2007-12-13

RAD51 is an important component of double-stranded DNA-repair mechanisms that interacts with both BRCA1 and BRCA2. A sin...

Kolas(Nadine K),Chapman(J Ross),Nakada(Shini… Science 2007-12-19

...BRCA1 to sites of damaged DNA. Here, we reveal that the ubiquitin ligase RNF8 mediates ubiquitin conjugation and 53BP1 a...

Yamane(Kenichi),Tateishi(Keisuke),Klose(Robe… Mol Cell 2007-05-08

...BRCA1.

Cao(Liu),Xu(Xiaoling),Cao(Longyue L),Wang(Ru… Carcinogenesis 2007-10-04

...Brca1) deletion and heterozygous for a p53-null mutation (Brca1(Delta11/Delta11)p53(+/-)), display premature aging and h...

Fedorova(O E),Liubchenko(L N),Paiadini(Iu G)… Mol Biol (Mosk) 2007-06-06

...BRCA1 gene were identified. The most prevailing mutation was 5382insC in BRCA1 gene (87.5% of all BRCA1 mutations OC pat...

Nagaraju(Ganesh),Scully(Ralph) DNA Repair (Amst) 2007-10-04

The hereditary breast and ovarian cancer predisposition genes, BRCA1 and BRCA2, participate in the repair of DNA double ...

Locke(Imogen),Kote-Jarai(Zsofia),Fackler(Mar… Breast Cancer Res 2007-05-10

...BRCA1/2 mutation status and/or breast cancer risk.,The pattern of CpG island hypermethylation within the promoter region...

Ramus(Susan J),Harrington(Patricia A),Pye(Ca… Hum Mutat 2007-06-21

...BRCA1 mutations, we used two different methods (mutation specific PCR and multiplex ligation-dependent probe amplificati...

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