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FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage…

Ling(Chen),Ishiai(Masamichi),Ali(Abdullah Ma… EMBO J 2007-10-04

...BRCA1 and BRCA2. The complex consists of eight FA proteins, including a ubiquitin ligase (FANCL) and a DNA translocase (...

Familial breast cancer in Costa Rica: an initial approach.

Ramírez Monge(Adriana),Gutiérrez-Espeleta(Gu… Rev Biol Trop 2007-07-30

...BRCA1 and BRCA2. Like other countries, Costa Rica possesses high rates of incidence and mortality for breast cancer. Acc...

A case of loss of heterozygosity in the BRCA2 gene of a borderline ovarian tumo…

Verbruggen(M B),Zweemer(R P),Piek(J M J),van… Int J Gynecol Cancer 2007-12-14

...BRCA1 and BRCA2 mutation carriers are described incidentally, while in patients with a BOT a germline BRCA1 or BRCA2 mut...

Estrogen receptor alpha is a putative substrate for the BRCA1 ubiquitin ligase.

Eakin(Catherine M),Maccoss(Michael J),Finney… Proc Natl Acad Sci U S A 2007-06-29

...BRCA1, is a ubiquitin ligase expressed in a wide range of tissues. However, inheritance of a single BRCA1 mutation signi...

Phenotype-directed analysis of genotype in early-onset, familial breast cancers.

Price(Gareth R),Armes(Jane E),Ramus(Susan J)… Pathology 2007-04-17

...BRCA1 germline mutation-associated tumours and commonly showed loss of chromosomal regions 5cent-5q13, 5q14-22 and 4q28-...

Factors associated with an individual's decision to withdraw from genetic testi…

Godard(Béatrice),Pratte(Annabelle),Dumont(Ma… Genet Test 2007-05-10

...BRCA1/2 mutations, when, and why they did so. Individuals who declined genetic testing were older, and a greater proport...

Prophylactic salpingo-oophorectomy in a series of 89 women carrying a BRCA1 or …

Laki(Fatima),Kirova(Youlia M),This(Pascale),… Cancer 2007-06-26

...BRCA1/2 mutation carriers, still needs to be reappraised.,In all, 89 BRCA1/BRCA2 mutation carriers underwent SO between ...

The cost-utility of magnetic resonance imaging for breast cancer in BRCA1 mutat…

Norman(Richard P A),Evans(D Gareth),Easton(D… Eur J Health Econ 2007-08-16

Recent evidence has investigated the cost-effectiveness of magnetic resonance imaging (MRI) in younger women with a BRCA...

BRCA1 regulates IFN-gamma signaling through a mechanism involving the type I IF…

Buckley(Niamh E),Hosey(Alison M),Gorski(Juli… Mol Cancer Res 2007-05-07

...BRCA1 transcriptional target and was also shown to be synergistically up-regulated by BRCA1 specifically in the presence...

Incorporating medical interventions into carrier probability estimation for gen…

Katki(Hormuzd A) BMC Med Genet 2007-04-09

...BRCA1 and BRCA2 based on her family history of breast and ovarian cancer. This new BRCAPRO is available for clinical use...

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