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Morphological features of TMPRSS2-ERG gene fusion prostate cancer.

Mosquera(J-M),Perner(S),Demichelis(F),Kim(R)… J Pathol 2007-06-18

...BRCA1 and BRCA2 mutations. The biological effect of TMPRSS2-ERG overexpression may drive pathways that favour these comm...

BRCA1a has antitumor activity in TN breast, ovarian and prostate cancers.

Yuli(C),Shao(N),Rao(R),Aysola(P),Reddy(V),Op… Oncogene 2007-10-19

...BRCA1 splice variant BRCA1a/p110 to induce apoptosis of human breast cancer cells. In the current study, stable expressi...

RAD51 up-regulation bypasses BRCA1 function and is a common feature of BRCA1-de…

Martin(Richard W),Orelli(Brian J),Yamazoe(Mi… Cancer Res 2007-12-12

...BRCA1-deficient tumorigenesis remain unclear. Given that BRCA1 is required for cell proliferation, suppressor mutations ...

Role of IFI16 in DNA damage and checkpoint.

Ouchi(Mutsuko),Ouchi(Toru) Front Biosci 2007-12-11

...BRCA1, breast cancer tumor suppressor protein. IFI16 has been identified as a target of IFNa and g and is a member of th...

Expression of the circadian clock genes Per1 and Per2 in sporadic and familial …

Winter(Sherry L),Bosnoyan-Collins(Lucine),Pi… Neoplasia 2007-12-27

...BRCA1 and the clock proteins Per1 and Per2, as well as the reported involvement of the circadian clock in the developmen...

SERS nanoparticles: a new optical detection modality for cancer diagnosis.

Sha(Michael Y),Xu(Hongxia),Penn(Sharron G),C… Nanomedicine (Lond) 2007-12-03

...BRCA1 and Her-2, along with examples of nucleic-acid detection. We present data on a novel homogeneous, single-tube, rap...

Germline BRCA1 mutation and survival analysis in familial breast cancer patient…

Vinodkumar(B),Syamala(V),Abraham(E K),Balakr… J Exp Clin Cancer Res 2007-12-26

...BRCA1 mutation carriers was also investigated. BRCA1 mutation was detected in 11 out of the 29 (38%) patients. Four diff...

High-resolution oligonucleotide array-CGH applied to the detection and characte…

Rouleau(E),Lefol(C),Tozlu(S),Andrieu(C),Guy(… Clin Genet 2007-12-03

...BRCA1 gene based on high-resolution oligonucleotide array-CGH technology. We designed a specific CGH array for the BRCA1...

Development and testing of a decision aid for breast cancer prevention for wome…

Metcalfe(K A),Poll(A),O'Connor(A),Gershman(S… Clin Genet 2007-12-03

For women who carry a mutation in BRCA1 or BRCA2, the risk of breast cancer is up to 87% by the age of 70. There are opt...

Identification and in silico analysis of functional SNPs of the BRCA1 gene.

Rajasekaran(R),Sudandiradoss(C),Doss(C Georg… Genomics 2007-12-07

...BRCA1 gene using computational methods. Of the total 477 SNPs, 65 were found to be nonsynonymous (ns) SNPs. Among the 14...

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