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Lymphoblasts of women with BRCA1 mutations are deficient in cellular repair of …

Rodriguez(Henry),Jaruga(Pawel),Leber(Dennis)… Biochemistry 2007-05-03

...BRCA1 and BRCA2 predispose women to a high risk of these cancers. Here, we show that lymphoblasts of women with BRCA1 mu...

The RAD51 135 G>C polymorphism modifies breast cancer and ovarian cancer risk i…

Jakubowska(Anna),Gronwald(Jacek),Menkiszak(J… Cancer Epidemiol Biomarkers P… 2007-04-03

...BRCA1 mutations. In addition, we were able to show that the site of the BRCA1 mutation does not influence the effect of ...

Sociocultural predictors of breast cancer risk perceptions in African American …

Brewster(Kiyona),Wileyto(E Paul),Kessler(Lis… Cancer Epidemiol Biomarkers P… 2007-04-03

...BRCA1 or BRCA1 (BRCA1/2) mutation and identified factors having significant independent associations with risk perceptio...

Genetic counseling and testing for breast cancer risk in African Americans.

Halbert(Chanita Hughes) LDI Issue Brief 2007-03-05

Genetic testing for susceptibility to breast and ovarian cancer (BRCA1/2 testing) has been available in clinical setting...

Prevention and early detection of ovarian cancer: mission impossible?

Bast(Robert C),Brewer(Molly),Zou(Changping),… Recent Results Cancer Res 2007-03-16

...BRCA1, BRCA2, and mismatch repair genes. More subtle genetic factors are being sought in women with apparently sporadic ...

Cancer genetics.

Chapman(Dianne D) Semin Oncol Nurs 2007-05-01

...BRCA1 and BRCA2.,Research and review articles and government internet sites.,The advances in molecular biology has enabl...

Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain…

Bogliolo(Massimo),Lyakhovich(Alex),Callén(El… EMBO J 2007-06-11

...BRCA1-dependent and cells deficient or depleted of H2AX show an FA-like phenotype, including an excess of chromatid-type...

The spectrum and incidence of BRCA1 pathogenic mutations in Slovak breast/ovari…

Konecny(M),Vizvaryova(M),Weismanova(E),Ilenc… Neoplasma 2007-06-28

...BRCA1 and BRCA2 account for the majority of hereditary breast/ovarian cancer cases. The analysis of BRCA1 gene was carri...

CYP17 genotype is associated with short menstrual cycles, early oral contracept…

Henningson(M),Johansson(U),Borg(A),Olsson(H)… Mol Hum Reprod 2007-06-21

...BRCA1/2 families compared with other high-risk women OR 2.92 (95% CI 1.49-5.73; P = 0.002, adjusted for family clusterin...

Determination of cancer risk associated with germ line BRCA1 missense variants …

Carvalho(Marcelo A),Marsillac(Sylvia M),Karc… Cancer Res 2007-03-15

...BRCA1 in combination with analysis of protein modeling based on the structure of BRCA1 BRCT domains. In addition, the in...

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