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Amplification of TOP2A and HER-2 genes in breast cancers occurring in patients …

Hagen(Anne I),Bofin(Anna M),Ytterhus(Borgny)… Acta Oncol 2007-06-01

...BRCA1 associated tumours only. In contrast, three of the BRCA1-associated tumours but none of the controls harboured TOP...

655Val and 1170Pro ERBB2 SNPs in familial breast cancer risk and BRCA1 alterati…

Tommasi(Stefania),Fedele(Vita),Lacalamita(Ro… Cell Oncol 2007-09-19

...BRCA1 alterations and clinical-pathological features of Caucasian breast cancer patients with familial history of breast...

Brca1 heterozygous mice have shortened life span and are prone to ovarian tumor…

Jeng(Y-M),Cai-Ng(S),Li(A),Furuta(S),Chew(H),… Oncogene 2007-10-24

BRCA1 mutation carriers have an 85% lifetime risk of breast cancer and 60% for ovarian cancer. BRCA1 facilitates DNA dou...

Evaluation of mathematical models for breast cancer risk assessment in routine …

Fasching(Peter A),Bani(Mayada R),Nestle-Kräm… Eur J Cancer Prev 2007-11-02

...BRCA1/2-mutations, p(mut), and p(life). In this study, the models are compared with Ford and Claus penetrance/frequency ...

Regulation of DNA repair in hypoxic cancer cells.

Bindra(Ranjit S),Crosby(Meredith E),Glazer(P… Cancer Metastasis Rev 2007-09-17

...BRCA1. Taken together, these findings reveal that hypoxia induces a unique cellular stress response involving an initial...

Age at menarche and menopause and breast cancer risk in the International BRCA1…

Chang-Claude(Jenny),Andrieu(Nadine),Rookus(M… Cancer Epidemiol Biomarkers P… 2007-06-05

...BRCA1 and BRCA2 carriers are unknown.,We assessed breast cancer risk in a large series of 1,187 BRCA1 and 414 BRCA2 carr...

Regulation of the BRCA1 promoter in ovarian surface epithelial cells and ovaria…

Graves(Marcia L),Zhou(Lixin),MacDonald(Gwen)… FEBS Lett 2007-06-29

As BRCA1 expression is often suppressed in sporadic ovarian carcinoma we characterized the regulation of the 231nt proxi...

Loss of nuclear BRCA1 protein staining in normal tissue cells derived from BRCA…

De Brakeleer(Sylvia),Bogdani(Marika),De Grèv… Mutat Res 2007-06-21

...BRCA1/2 mutation carriers, sporadic breast cancer patients and controls were prepared for BRCA1 immunocytochemistry. We ...

Aberrant expression of TopBP1 in breast cancer.

Going(J J),Nixon(C),Dornan(E S),Boner(W),Don… Histopathology 2007-05-24

...BRCA1) and has homology with BRCA1 over the carboxyl terminal half of the protein. The aim of this study was to determin...

Breast carcinoma with basal differentiation: a proposal for pathology definitio…

Rakha(E A),El-Sayed(M E),Green(A R),Paish(E … Histopathology 2007-05-24

...BRCA1, P-cadherin and myoepithelial markers (smooth muscle actin and p63) were studied in a well-characterized series of...

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