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Screening for BRCA1 and BRCA2 mutations in Eastern Finnish breast/ovarian cance…

Hartikainen(J M),Kataja(V),Pirskanen(M),Arff… Clin Genet 2007-11-07

...BRCA1/BRCA2 mutations. This screen also provides further evidence for the presumption that the majority of Finnish BRCA1...

Validity of models for predicting BRCA1 and BRCA2 mutations.

Parmigiani(Giovanni),Chen(Sining),Iversen(Ed… Ann Intern Med 2007-10-05

Deleterious mutations of the BRCA1 and BRCA2 genes confer susceptibility to breast and ovarian cancer. At least 7 models...

PARP inhibitor development for systemic cancer targeting.

Zaremba(Tomasz),Curtin(Nicola Jane) Anticancer Agents Med Chem 2007-11-02

...BRCA1 and BRCA2.

RAD51 135G>C polymorphism and risk of familial breast cancer in a South America…

Jara(Lilian),Acevedo(Monica L),Blanco(Rafael… Cancer Genet Cytogenet 2007-11-09

...BRCA1 and BRCA2. Few studies have investigated the role of RAD51 gene variations in familial BC. To detect potential nov...

Society of Gynecologic Oncologists Education Committee statement on risk assess…

Lancaster(Johnathan M),Powell(C Bethan),Kauf… Gynecol Oncol 2007-12-12

...BRCA1 or BRCA2, associated with Hereditary Breast/Ovarian Cancer syndrome, have up to an 85% lifetime risk of breast can...

BRCA1 and BRCA2 genetic testing in Hispanic patients: mutation prevalence and e…

Vogel(Kristen J),Atchley(Deann P),Erlichman(… J Clin Oncol 2007-11-05

The BRCAPRO model, used to predict a family's likelihood of carrying a BRCA1 or BRCA2 mutation, was designed using mutat...

[Predictive genetic testing for hereditary breast cancer and hereditary nonpoly…

Heyll(U),Slany(E) Versicherungsmedizin 2007-11-13

...BRCA1 - and BRCA2- mutations and hereditary nonpolyposis colorectal cancer (HNPCC). The observation of such conditions c...

Expression of MDR1 in epithelial ovarian cancer and its association with diseas…

Lu(Lingeng),Katsaros(Dionyssios),Wiley(Andre… Oncol Res 2007-12-06

...BRCA1, and to examine the association of MDR1 expression with ovarian cancer prognosis. A primary ovarian cancer cohort ...

The ePHD protein SPBP interacts with TopBP1 and together they co-operate to sti…

Sjøttem(Eva),Rekdal(Cecilie),Svineng(Gunbjør… Nucleic Acids Res 2007-12-27

...BRCA1 carboxy-terminal (BRCT) domains and is involved in DNA replication, DNA damage responses and in the regulation of ...

A systematic genetic assessment of 1,433 sequence variants of unknown clinical …

Easton(Douglas F),Deffenbaugh(Amie M),Pruss(… Am J Hum Genet 2007-11-27

...BRCA1 and BRCA2 is becoming an increasingly important part of clinical practice. Classification of rare nontruncating se...

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