...BRCA1 gene were identified. The most prevailing mutation was 5382insC in BRCA1 gene (87.5% of all BRCA1 mutations OC pat...
...BRCA1 or BRCA2 mutations, or carriers of mismatch repair gene mutations in the hereditary nonpolyposis colorectal cancer...
...BRCA1 C-terminal (BRCT) domain of TopBP1 interacts with a protein fragment of PARP-1 in vitro containing the DNA-binding...
As sequence analysis for BRCA1 and BRCA2 mutations is both time- and cost-intensive, current strategies often include sc...
...BRCA1 protein level. Since DHA influences the product of a major tumour suppressor gene, this finding may contribute to ...
...BRCA1 and BRCA2 based on her family history of breast and ovarian cancer. This new BRCAPRO is available for clinical use...
...BRCA1, is a ubiquitin ligase expressed in a wide range of tissues. However, inheritance of a single BRCA1 mutation signi...
...BRCA1 mutations, we used two different methods (mutation specific PCR and multiplex ligation-dependent probe amplificati...
The hereditary breast and ovarian cancer predisposition genes, BRCA1 and BRCA2, participate in the repair of DNA double ...
...BRCA1 and BRCA2. The complex consists of eight FA proteins, including a ubiquitin ligase (FANCL) and a DNA translocase (...
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