...BRCA1) are associated with an increased risk of breast and ovarian cancers. BRCA1 participates in the cellular DNA damag...
...BRCA1, through its helicase domain. Genetic studies reveal that FANCJ helicase activity and MLH1 binding, but not BRCA1 ...
...BRCA1 Gln(356)Arg is not in strong linkage disequilibrium with other BRCA1 coding SNPs or any known HapMap SNP on chromo...
...BRCA1 or BARD1, which together function as an E3 ligase that can ubiquitinate arrested RNAPII. Treatment with the protea...
...BRCA1/2 conventional mutation screening. One hundred and seventy-seven probands were investigated for germline BRCA1/2 m...
BRCA1 and BRCA2 germline mutations contribute to a significant number of familial and hereditary breast and/or ovarian c...
The frequency and the type of BRCA1 mutations vary widely and might have different geographic and ethnic distribution. M...
...BRCA1 and BRCA2. The genetic analysis of these genes is complex and expensive essentially because their length. Neverthe...
...BRCA1 phosphorylation. Unlike wild-type BRCA1, expression of the PP1 non-binding mutant BRCA1 protein in BRCA1-deficient...
...BRCA1) are not fully characterised. By studying regulation of endogenous BRCA1 in human epithelial cell lines and during...
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