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CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage respon…

Kim(Hongtae),Huang(Jun),Chen(Junjie) Nat Struct Mol Biol 2007-10-02

...BRCA1-interacting protein. CCDC98 colocalizes with BRCA1 and is required for the formation of BRCA1 foci in response to ...

Cofactor of BRCA1 modulates androgen-dependent transcription and alternative sp…

Sun(Jianlong),Blair(Ashley L),Aiyar(Sarah E)… J Steroid Biochem Mol Biol 2007-11-27

...BRCA1 (COBRA1), a subunit of the negative elongation factor (NELF), binds to estrogen receptor alpha (ERalpha) and modul...

Germline E-cadherin mutations in familial lobular breast cancer.

Masciari(S),Larsson(N),Senz(J),Boyd(N),Kaura… J Med Genet 2007-11-29

...BRCA1 or BRCA2 mutation, and reported no personal or family history of diffuse gastric cancer. The full coding sequence ...

Inhibition of potential lethal damage repair and related gene expression after …

Yashiro(Tomoyasu),Koyama-Saegusa(Kumiko),Ima… J Radiat Res 2007-12-06

...BRCA1, MRE11A, XRCC3, CHEK1, MLH1, CCNB1, CCNB2 and LIG4. We conclude that PCNA could be a likely candidate gene for PLD...

A mutation in the 5' untranslated region of the BRCA1 gene in sporadic breast c…

Wang(J),Lu(C),Min(D),Wang(Z),Ma(X) J Int Med Res 2007-09-27

...BRCA1 protein in breast tumour samples was evaluated using immunohistochemistry. The mutated 5' UTR of BRCA1 resulted in...

DNA profiling of primary serous ovarian and fallopian tube carcinomas with arra…

Nowee(M E),Snijders(A M),Rockx(D A P),de Wit… J Pathol 2007-12-07

...BRCA1-mutated FTC shared common denominators with the sporadic tumours. In conclusion, the data suggest that serous OVCA...

Genetic and functional analysis of CHEK2 (CHK2) variants in multiethnic cohorts.

Bell(Daphne W),Kim(Sang H),Godwin(Andrew K),… Int J Cancer 2007-11-30

...BRCA1 as a substrate. The germline CHEK2-1100delC mutation was present among 8/1,646 (0.5%) sporadic, 2/400 (0.5%) early...

Attenuated DNA damage repair by trichostatin A through BRCA1 suppression.

Zhang(Yin),Carr(Theresa),Dimtchev(Alexandre)… Radiat Res 2007-09-14

...BRCA1. The involvement of BRCA1 was further demonstrated by expressing ectopic wild-type BRCA1 in a BRCA1 null cell line...

Haplotype-based analysis of common variation in the acetyl-coA carboxylase alph…

Sinilnikova(Olga M),McKay(James D),Tavtigian… Cancer Epidemiol Biomarkers P… 2007-05-03

...BRCA1. We used a comprehensive haplotype analysis to examine the contribution of the ACC-alpha common genetic variation ...

High-resolution genomic profiles of breast cancer cell lines assessed by tiling…

Jönsson(Göran),Staaf(Johan),Olsson(Eleonor),… Genes Chromosomes Cancer 2007-06-08

...BRCA1 mutation carriers and MDA-MB-231, were of basal-like subtype and characterized by a high frequency of low-level ga...

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