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Quality of life after contralateral prophylactic mastectomy in newly diagnosed …

Tercyak(Kenneth P),Peshkin(Beth N),Brogan(Ba… J Clin Oncol 2007-01-25

Recent studies indicate that high-risk breast cancer patients (ie, women who carry mutations in BRCA1/2 genes) who opt f...

BRCA1 does not paint the inactive X to localize XIST RNA but may contribute to …

Pageau(Gayle J),Hall(Lisa L),Lawrence(Jeanne… J Cell Biochem 2007-04-16

...BRCA1 and XIST RNA across the Xi raised the possibility a direct role of BRCA1 in localizing XIST. We report here that B...

Inhibition of BACH1 (FANCJ) helicase by backbone discontinuity is overcome by i…

Gupta(Rigu),Sharma(Sudha),Doherty(Kevin M),S… Nucleic Acids Res 2007-01-25

...BRCA1 associated C-terminal helicase (BACH1) associated with breast cancer has been implicated in double strand break (D...

SNPs typing by base-discriminating fluorescence DNA probe.

Okamoto(Akimitsu),Tainaka(Kazuki),Ochi(Yuji)… Nucleic Acids Symp Ser (Oxf) 2007-06-12

...BRCA1 gene with PCR products amplified by an asymmetric PCR. A combination of PyU- and PyC-containing BDF probes clearly...

Methyl group metabolism gene polymorphisms as modifier of breast cancer risk in…

Pepe(C),Guidugli(L),Sensi(E),Aretini(P),D'An… Breast Cancer Res Treat 2007-09-19

BRCA1 and 2 are major cancer susceptibility genes but their penetrance is highly variable. The folate metabolism plays a...

Late toxicity is not increased in BRCA1/BRCA2 mutation carriers undergoing brea…

Shanley(Susan),McReynolds(Kate),Ardern-Jones… Clin Cancer Res 2007-11-28

To undertake the first substantial clinical study of breast radiotherapy toxicity in BRCA1 and BRCA2 mutation carriers i...

Acute chemotherapy-related toxicity is not increased in BRCA1 and BRCA2 mutatio…

Shanley(Susan),McReynolds(Kate),Ardern-Jones… Clin Cancer Res 2007-11-28

To evaluate acute toxicity induced by chemotherapy for breast cancer in a retrospective study of 62 BRCA1/2 mutation car...

Activation of the Fanconi anemia/BRCA pathway and recombination repair in the c…

Dunn(Jessica),Potter(Marisa),Rees(Adam),Rüng… Cancer Res 2007-01-10

...BRCA1, colocalized with FANCD2 foci. We suggest that in response to UV light, when nucleotide excision repair failed to ...

BRCA1 foci in normal S-phase nuclei are linked to interphase centromeres and re…

Pageau(Gayle J),Lawrence(Jeanne B) J Cell Biol 2007-02-13

...BRCA1) forms foci at sites of induced DNA damage, but any significance of these normal S-phase foci is unknown. BRCA1 di...

BRCA2 mutation-associated breast cancers exhibit a distinguishing phenotype bas…

Bane(Anita L),Beck(Jeanne C),Bleiweiss(Ira),… Am J Surg Pathol 2007-02-06

A distinct morphologic and molecular phenotype has been reported for BRCA1-associated breast cancers; however, the pheno...

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