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Prolonged Mitogen-Activated Protein Kinase Kinase (MEK) Inhibition Induces Incr…

Ji(K),Callaghan(JF),Ridella(TJ),Mattingly(RR) Cells 2026-02-28

...NF1s) are benign tumors caused by the complete loss of function of the NF1 gene, which encodes a negative regulator of t...

Pathogenicity Prediction of Missense Variations in Hereditary Cancer Genes.

Akyerli(CB),Gerdan(G),Bülbül(A),Keskin-Karak… Int J Mol Sci 2026-03-07

...NF1, FH, and MLH1 genes. By combining gene-specific training with 3D structural information, HerCanPred provides a robus...

Driving proteomic imbalance in malignancy provokes proteomic catastrophe and co…

Ram(BM),Shriwas(O),Xu(M),Chuang(KH),Dai(C) bioRxiv 2026-04-09

...NF1)-deficient malignant peripheral nerve sheath tumor (MPNST) cells, HSF1 loss induces widespread protein polyubiquitin...

Case Report: Somatic NF2 mutation in a vestibular schwannoma arising in a patie…

Shogaku(M),Yamada(H),Yamada(S),Fujinami(R),Y… Front Oncol None

Neurofibromatosis type 1 (NF1) and vestibular schwannoma are genetically and clinically distinct entities, with vestibul...

A rare case report of solitary neurofibroma arising in the male breast.

Parkhurst(EL),Chan(SM) Int J Surg Case Rep 2026-03-00

...NF1). This report aims to present the case of a solitary neurofibroma in the breast of a male patient in the absence of ...

Real-world outcomes for selumetinib in pediatric patients with neurofibromatosi…

Nishida(Y),Kitajima(A),Ishii(T) Neurooncol Adv None

...NF1) and plexiform neurofibromas (PN) in Japan. The surveillance was initiated on November 16, 2022, the launch date of ...

Adult patient and caregiver perspectives on the impact of NF1-PN: Insights from…

Nghiemphu(PL),Cordova(CL),Bowling(A),Crites(… Neurooncol Adv None

...NF1, including pain disorders, psychiatric disorders, and chronic migraines. NF1-PN impacted daily living, work, school,...

Building a framework for adolescent and young adult transition of care for pati…

Schwartzbaum(D),Dinh(C),Borja(NA),Dhir(A),Co… Front Oncol None

...NF1 and NF2-SWN. Having an AYA HCT model can decrease gaps in care and improve survival. We review the literature on NF1...

Clinical and molecular features of primary gliosarcoma with digital spatial who…

Wood(MD),Zangirolani(G),Lee(J),Hakar(MH),Nef… Brain Pathol 2026-09-00

...NF1 mutation compared to glioblastomas in next-generation sequencing analysis. Digital spatial whole-transcriptome analy...

Durable disease control in a radiation-induced high-grade glioma harboring NF1 …

Sherief(M),Fatteh(M),Wehr(J),Holdhoff(M),Ebe… Neurooncol Adv None

...NF1 mutation and a gain-of-function PTPN11 mutation, two convergent alterations in the MAPK pathway. Based on these find...

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