Castor(Dennis),Nair(Nidhi),Déclais(Anne-Céci… Mol Cell 2014-01-17

...SLX4 scaffold, hinting at possible cooperation. However, the cellular roles of mammalian SLX1 are not yet known. Here, w...

Wyatt(Haley D M),Sarbajna(Shriparna),Matos(J… Mol Cell 2014-01-17

...SLX4, MUS81-EME1, and GEN1, define two pathways of HJ resolution in human cells. One pathway is mediated by GEN1, wherea...

Garner(Elizabeth),Kim(Yonghwan),Lach(Francis… Cell Rep 2014-07-21

...SLX4-null cells to examine the requirements for HJ resolution in vivo. Lack of BLM and SLX4 or GEN1 and SLX4 is syntheti...

Wilson(Jamie S J),Tejera(Agueda M),Castor(De… Cell Rep 2014-06-12

...SLX4 forms foci in human cells even without DNA damage. Using several approaches, we show that most, but not all, SLX4 f...

Wan(Bingbing),Yin(Jinhu),Horvath(Kent),Sarka… Cell Rep 2014-06-12

...SLX4 and associated nucleases depend on the SLX4-endonuclease and SLX4-TRF2 interactions and the protein levels of SLX4 ...

Rass(Ulrich) Chromosoma 2014-06-26

...Slx4/SLX1-SLX4 (FANCP) have been implicated in the resolution of branched DNA intermediates. It is becoming increasingly...

Saito(Takamune T),Lui(Doris Y),Kim(Hyun-Min)… PLoS Genet 2014-01-08

...SLX4, a key scaffold for nucleases. Analysis of synthetic mitotic defects revealed that MUS-81 and SLX-1, but not XPF-1 ...

Klein Douwel(Daisy),Boonen(Rick A C M),Long(… Mol Cell 2014-07-23

...SLX4/FANCP to carry out the unhooking incisions. Efficient recruitment of XPF-ERCC1 and SLX4 to the ICL depends on FANCD...

Hodskinson(Michael R G),Silhan(Jan),Crossan(… Mol Cell 2014-07-23

...SLX4 and its associated nucleases act in DNA crosslink repair. Here, we uncover consequences of mouse Slx4 deficiency an...

Kurian(Allison W),Hare(Emily E),Mills(Meredi… J Clin Oncol 2014-08-15

...SLX4 among 141 women without BRCA1/2 mutations. Fourteen participants carried 15 pathogenic variants, warranting a possi...