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DNA methylation restrains transposons from adopting a chromatin signature permi…

Zamudio(Natasha),Barau(Joan),Teissandier(Aur… Genes Dev 2015-09-03

...SPO11-dependent double-strand breaks and recruitment of the DMC1 repair enzyme in Dnmt3L(-/-) meiotic cells, whereas the...

Gradual implementation of the meiotic recombination program via checkpoint path…

Joshi(Neeraj),Brown(M Scott),Bishop(Douglas … Mol Cell 2015-06-15

...Spo11-induced double-strand breaks (DSBs) are processed into crossovers, ensuring segregation of homologous chromosomes ...

Elevated mutation rate during meiosis in Saccharomyces cerevisiae.

Rattray(Alison),Santoyo(Gustavo),Shafer(Bren… PLoS Genet 2015-06-30

...Spo11, the protein that introduces the meiosis specific DSBs. To examine associated recombination we selected for random...

Epigenetic control of meiotic recombination in plants.

Yelina(Natasha),Diaz(Patrick),Lambing(Christ… Sci China Life Sci 2015-12-31

...Spo11 endonuclease. These breaks can be repaired as crossovers that result in reciprocal exchange between chromosomes. T...

Tel1(ATM)-mediated interference suppresses clustered meiotic double-strand-brea…

Garcia(Valerie),Gray(Stephen),Allison(Rachal… Nature 2015-04-30

...Spo11, the evolutionarily conserved topoisomerase-like protein, but how these DSBs are distributed relatively uniformly ...

Drosophila Yemanuclein associates with the cohesin and synaptonemal complexes.

Meyer(Régis E),Algazeery(Ahmed),Capri(Michèl… J Cell Sci 2015-09-01

...Spo11 homolog mei-W68, modified a yem(1) dominant effect on crossover distribution, suggesting that Yem has an early rol...

Condensin suppresses recombination and regulates double-strand break processing…

Li(Ping),Jin(Hui),Yu(Hong-Guo) Mol Biol Cell 2015-06-10

...Spo11-mediated rDNA breaks, and it promotes DSB processing to ensure proper chromosome segregation. Condensin is unneces...

Homeostatic regulation of meiotic DSB formation by ATM/ATR.

Cooper(Tim J),Wardell(Kayleigh),Garcia(Valer… Exp Cell Res 2015-02-04

...Spo11. This review seeks to explore and address how cells utilise ATM/ATR pathways to regulate Spo11-DSB formation, esta...

Study of single nucleotide polymorphism (rs28368082) in SPO11 gene and its asso…

Ghalkhani(Esmat),Sheidai(Masoud),Gourabi(Ham… J Assist Reprod Genet 2015-05-27

The present study is a case-control analysis of a SNP (rs28368082) in exon 7 of the SPO11 gene and its possible associat...

Which one is the real matchmaker for the pair?

Han(Chunsheng) Asian J Androl 2015-05-21

...SPO11, an evolutionarily conserved type 2 isomerase responsible for generating DNA double-strand breaks (DSBs), nor SUN1...

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