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Crystal structure of the BARD1 BRCT domains.

Birrane(Gabriel),Varma(Ashok K),Soni(Aditi),… Biochemistry 2007-08-23

The interaction of the breast tumor suppressor BRCA1 with the protein BARD1 results in the formation of a heterodimeric ...

Identification of BARD1 splice-isoforms involved in human trophoblast invasion.

Li(Lin),Cohen(Marie),Wu(Jianyu),Sow(Mamadou … Int J Biochem Cell Biol 2007-09-27

...BRCA1-binding protein, acts in conjunction with BRCA1 as ubiquitin ligase. BARD1 and BRCA1 form a stable heterodimer and...

BRCA1 control of steroid receptor ubiquitination.

Heine(George F),Parvin(Jeffrey D) Sci STKE 2007-09-24

...BRCA1, as part of a heterodimer with BARD1 (BRCA1-associated RING domain 1), is critical for its role as a tumor suppres...

Evidence for common ancestral origin of a recurring BRCA1 genomic rearrangement…

Weitzel(Jeffrey N),Lagos(Veronica I),Herzog(… Cancer Epidemiol Biomarkers P… 2007-10-11

...BRCA1 protein.,We identified and characterized a novel large BRCA1 deletion in five unrelated families-four of Mexican a...

Oral contraceptives and breast cancer risk in the international BRCA1/2 carrier…

Brohet(Richard M),Goldgar(David E),Easton(Do… J Clin Oncol 2007-09-11

...BRCA1/2 carriers. PATIENTS AND METHODS In the International BRCA1/2 Carrier Cohort study (IBCCS), a retrospective cohort...

Chromogenic and fluorescent in situ hybridization in breast cancer.

Lambros(Maryou B K),Natrajan(Rachael),Reis-F… Hum Pathol 2007-09-11

...BRCA1 and BRCA2) on our understanding of breast cancer.

New insights into breast cancer genetics and impact on patient management.

Rosman(Diana S),Kaklamani(Virginia),Pasche(B… Curr Treat Options Oncol 2007-11-13

...BRCA1 and BRCA2. Such genes may also modify the penetrance of the BRCA1 and BRCA2 genes. In the next decade, screening f...

CCDC98 targets BRCA1 to DNA damage sites.

Liu(Zixing),Wu(Jiaxue),Yu(Xiaochun) Nat Struct Mol Biol 2007-10-02

...BRCA1 translocation. Here we identify another component, CCDC98, in the BRCA1-RAP80 complex. CCDC98 mediates BRCA1's ass...

CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage respon…

Kim(Hongtae),Huang(Jun),Chen(Junjie) Nat Struct Mol Biol 2007-10-02

...BRCA1-interacting protein. CCDC98 colocalizes with BRCA1 and is required for the formation of BRCA1 foci in response to ...

The disappearing Barr body in breast and ovarian cancers.

Pageau(Gayle J),Hall(Lisa L),Ganesan(Shridar… Nat Rev Cancer 2007-10-01

...BRCA1 and Xi might reflect a general relationship between BRCA1 and heterochromatin, which could connect BRCA1 to both e...

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