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TP53 BRCA1 CRISPR single-cell cancer

DelloRusso(Christiana),Welcsh(Piri L),Wang(W… Mol Cancer Res 2007-03-01

...BRCA1 plays a major role in the DNA damage response pathway. The lack of well-characterized human BRCA1-null cell lines ...

Trecate(Giovanna),Vergnaghi(Daniele),Manouki… Tumori 2007-02-20

Women with BRCA1 or BRCA2 germline mutations have an elevated risk of developing breast and/or ovarian cancer. Because o...

Rosell(R),Moran(T),Fernanda Salazar(M),Mende… Rev Mal Respir 2007-06-27

...BRCA1 mRNA expression is a differential modulator of chemotherapy sensitivity. Low levels predict cisplatin sensitivity ...

Foster(C),Watson(M),Eeles(R),Eccles(D),Ashle… Br J Cancer 2007-05-04

...BRCA1/2 mutation. One hundred and ninety-three out of 285 (70% response) participants at nine UK clinical genetics centr...

Dubey(Sylvain),Salamin(Nicolas),Ohdachi(Sato… Mol Phylogenet Evol 2007-08-27

...BRCA1 and ApoB in shrews taxa (Eulipotyphla, family Soricidae). The aim was to study the relationships at higher taxonom...

Hao(Lu),ElShamy(Wael M) Int J Cancer 2007-06-18

...BRCA1-IRIS induces Cyclin D1 overexpression and increases cell proliferation. BRCA1-IRIS alone or in complex with steroi...

Osorio(A),Milne(R L),Honrado(E),Barroso(A),D… Hum Mutat 2007-06-21

...BRCA1 and BRCA2; however, the strongest evidence tends to come from segregation analysis and observed cooccurrence with ...

Wu(Wenwen),Nishikawa(Hiroyuki),Hayami(Ryosuk… Cancer Res 2007-03-01

...BRCA1-dependent manner. RPB8 interacted with BRCA1-BARD1 and was polyubiquitinated by BRCA1-BARD1 in vivo and in vitro. ...

Erkko(Hannele),Xia(Bing),Nikkilä(Jenni),Schl… Nature 2007-04-11

BRCA1, BRCA2 and other known susceptibility genes account for less than half of the detectable hereditary predisposition...

Tong(W M),Yang(Y G),Cao(W H),Galendo(D),Frap… Oncogene 2007-07-09

...BRCA1 recruitment to the sites of DNA damage in PME cells. PARP-1 complementation partly rescues the defective DNA damag...

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