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Effectiveness of preventive interventions in BRCA1/2 gene mutation carriers: a …

Bermejo-Pérez(M J),Márquez-Calderón(S),Llano… Int J Cancer 2007-08-06

...BRCA1/2 genes, in terms of reducing breast and gynaecological cancer incidence and/or mortality. A search for relevant a...

An international initiative to identify genetic modifiers of cancer risk in BRC…

Chenevix-Trench(Georgia),Milne(Roger L),Anto… Breast Cancer Res 2007-06-13

...BRCA1 and 5,000 BRCA2 mutation carriers. Initial efforts by CIMBA to identify modifiers of breast cancer risk for BRCA1 ...

ABT-888, an orally active poly(ADP-ribose) polymerase inhibitor that potentiate…

Donawho(Cherrie K),Luo(Yan),Luo(Yanping),Pen… Clin Cancer Res 2007-07-11

...BRCA1 deletion and BRCA2 mutation), ABT-888 potentiated cisplatin, carboplatin, and cyclophosphamide, causing regression...

New roads to FA/BRCA pathway: H2AX.

Lyakhovich(Alex),Surrallés(Jordi) Cell Cycle 2007-08-07

...BRCA1 mediates the recruitment of FANCD2 by gammaH2AX to damaged chromatin and cells deficient or depleted of H2AX exhib...

Humoral immune responses to MUC1 in women with a BRCA1 or BRCA2 mutation.

Hermsen(B B J),Verheijen(R H M),Menko(F H),G… Eur J Cancer 2007-11-20

...BRCA1/2 carriers, attending the Familial Cancer Clinic of the VU University Medical Centre, and from 370 age-matched hea...

Large genomic rearrangement in BRCA1 and BRCA2 and clinical characteristics of …

Tchou(Julia),Ward(M Renee),Volpe(Patricia),P… Clin Breast Cancer 2007-08-24

...BRCA1 and BRCA2, respectively. In the remaining 26 men, we screened for large genomic rearrangements in BRCA1 and BRCA2 ...

Promoter hypermethylation of TMS1, BRCA1, ERalpha and PRB in serum and tumor DN…

Mirza(Sameer),Sharma(Gayatri),Prasad(Chandra… Life Sci 2007-08-29

...BRCA1, ERalpha and PRB was determined in invasive ductal carcinoma of breast and paired serum DNA. Of the 50 breast canc...

Cobaltous chloride and hypoxia inhibit aryl hydrocarbon receptor-mediated respo…

Khan(Shaheen),Liu(Shengxi),Stoner(Matthew),S… Toxicol Appl Pharmacol 2007-09-27

...BRCA1 (an enhancer of AhR-mediated transactivation in breast cancer cells) was significantly decreased and this contribu...

Results of an intervention for individuals and families with BRCA mutations: a …

McKinnon(Wendy),Naud(Shelly),Ashikaga(Taka),… J Genet Couns 2007-12-26

...BRCA1/2 carriers in our region. The retreat included educational updates about medical management, genetic privacy and d...

Moesin expression is a marker of basal breast carcinomas.

Charafe-Jauffret(Emmanuelle),Monville(Floren… Int J Cancer 2007-10-29

...BRCA1-associated breast cancers (BRCA1-BCs), respectively. Moesin was strongly expressed in MBCs (87%; p = 2.4 x 10(-5))...

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