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Effect of mammography on breast cancer risk in women with mutations in BRCA1 or…

Goldfrank(Deborah),Chuai(Shannon),Bernstein(… Cancer Epidemiol Biomarkers P… 2007-06-12

Women who carry mutations in either the BRCA1 or BRCA2 genes are at risk for early-onset breast cancer and are recommend...

Prognosis of early-onset breast cancer based on BRCA1/2 mutation status in a Fr…

Bonadona(Valérie),Dussart-Moser(Sophie),Voir… Breast Cancer Res Treat 2007-05-16

...BRCA1/2 mutations (median follow-up: 82 months). We compared tumour characteristics and survival rates between 21 BRCA1/...

Uncertainty in BRCA1 cancer susceptibility testing.

Baty(Bonnie J),Dudley(William N),Musters(Adr… Am J Med Genet C Semin Med Ge… 2007-01-29

...BRCA1 mutation rated uncertainty about 12 items on a five-point Likert scale before and 1 month after genetic counseling...

Conditional inactivation of Brca1 in the mouse ovarian surface epithelium resul…

Clark-Knowles(Katherine V),Garson(Kenneth),J… Exp Cell Res 2007-02-09

...BRCA1 dysfunction. Using mice with conditional expression of Brca1, we inactivated Brca1 in the murine OSE and demonstra...

Epigenetic inactivation of BRCA1 is associated with aberrant expression of CTCF…

Butcher(Darci T),Rodenhiser(David I) Eur J Cancer 2007-03-26

...BRCA1, CTCF and DNMT3b methyltransferase genes along with BRCA1 promoter methylation to better define the epigenetic eve...

Cancer-related mutations in BRCA1-BRCT cause long-range structural changes in p…

Gough(Craig A),Gojobori(Takashi),Imanishi(Ta… Proteins 2007-02-19

...BRCA1 (BRCA1-BRCT) abolish its tumor suppressor function by disrupting interactions with other proteins such as BACH1. M...

Predictors and outcomes of contralateral prophylactic mastectomy among breast c…

Graves(Kristi D),Peshkin(Beth N),Halbert(Cha… Breast Cancer Res Treat 2007-10-15

...BRCA1 or BRCA2 (BRCA1/2) mutation are at risk of developing contralateral breast cancer. To reduce the risk of contralat...

Studies on the methylation status of CpG sequences located in promoters of sele…

Fabianowska-Majewska(K),Kordek(R),Krawczyk(B) Nucleosides Nucleotides Nucle… 2007-01-23

...BRCA1 promoter in 95%, and (iii) nonmethylated E-cadherin promoter in 90%. Fifty-eight percent of the patients with nonm...

Alteration of DNA methylation status in K562 and MCF-7 cancer cell lines by nuc…

Krawczyk(B),Fabianowska-Majewska(K) Nucleosides Nucleotides Nucle… 2007-01-23

...BRCA1, E-cadherin, PTEN, and APC) were estimated using methylation-sensitive restriction analysis (MSRA) in K562 cells (...

Methylenetetrahydrofolate reductase polymorphisms modify BRCA1-associated breas…

Jakubowska(Anna),Gronwald(Jacek),Menkiszak(J… Breast Cancer Res Treat 2007-10-15

...BRCA1 mutation carriers. The study included 319 breast cancer cases, 146 ovarian cancer cases and 290 controls unaffecte...

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