BRCA1 and BRCA2 mutations increase breast and ovarian cancer risks substantially enough to warrant risk reduction surger...
The BRCA1 gene product helps to maintain genomic integrity through its participation in the cellular response to DNA dam...
...BRCA1 and BRCA2 to estimate DCIS prevalence and incidence in known BRCA-positive women compared with high-risk women who...
...BRCA1 and BRCA2 genes. A novel BRCA2 frame-shift mutation, 3951del3insAT, which produces a protein truncated at codon 12...
...BRCA1-BRCA2 samples with RBF kernel of SVM.,We have developed a java GUI application that allows SVM users to perform SV...
...BRCA1/BRCA 2 negative hereditary breast cancer from independent families and 121 age-matched healthy controls were analy...
Deficiency in either of the breast cancer susceptibility proteins BRCA1 or BRCA2 induces profound cellular sensitivity t...
...BRCA1 or ATM are 2- to 4-fold more sensitive to CDK inhibitors. These data suggest that inhibitors of CDK2 can be applie...
...BRCA1 and BRCA2, respectively. BRCA1 mutations were significantly more common in White (2.9%) versus Black (1.4%) cases ...
...BRCA1, and p53 TSGs. The work described is valuable because it allows TSG mammary cancer susceptibility to be quantified...
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